The amyloidoses are a group of systemic diseases characterized by organ deposition of
misfolded protein fragments of diverse origins. The natural history of the disease …

Transthyretin cardiac amyloidosis (ATTR‐CA) demonstrates progressive, potentially fatal,
and infiltrative cardiomyopathy caused by extracellular deposition of transthyretin‐derived …

The systemic amyloidoses are a family of diseases induced by misfolded or misassembled
proteins. Extracellular deposition of these proteins as soluble or insoluble cross-sheets …

Background This guideline has been developed jointly by the European Society of
Haematology and International Society of Amyloidosis recommending non-transplant …

Light chain (AL) amyloidosis is caused by a usually small plasma cell clone producing a
misfolded light chain that deposits in tissues. Survival is mostly determined by the severity of …

Transthyretin-cardiac amyloidoses (ATTR-CA) are an underdiagnosed but increasingly
recognized cause of heart failure. Extracellular deposition of fibrillary proteins into tissues …

The conversion of proteins from their native state to misfolded oligomers is associated with,
and thought to be the cause of, a number of human diseases, including Alzheimer's disease …

Background Carpal tunnel syndrome (CTS) and spinal canal stenosis can be frequently
observed in the medical history of patients with transthyretin amyloidosis (ATTR), both in the …

The introduction of novel agents in the management of multiple myeloma and related
plasma cell dyscrasias has changed our treatment approaches and subsequently the …

Cardiac involvement has a profound effect on the prognosis of patients with systemic
amyloidosis. Therapeutic methods for suppressing the production of causative proteins have …