The what and where of adding channel noise to the Hodgkin-Huxley equations

JH Goldwyn, E Shea-Brown - PLoS computational biology, 2011 - journals.plos.org
Conductance-based equations for electrically active cells form one of the most widely
studied mathematical frameworks in computational biology. This framework, as expressed …

Signal coding in cochlear implants: exploiting stochastic effects of electrical stimulation

JT Rubinstein, R Hong - Annals of Otology, Rhinology & …, 2003 - journals.sagepub.com
Speech perception in quiet with cochlear implants has increased substantially over the past
17 years. If current trends continue, average monosyllabic word scores will be nearly 80 …

[图书][B] Chemical biophysics: quantitative analysis of cellular systems

DA Beard, H Qian - 2008 - biomed.bas.bg
CHEMICAL BIOPHYSICS QUANTITATIVE ANALYSIS OF CELLULAR SYSTEMS Page 1 102
DANIEL A. BEARD, HONG QIAN CHEMICAL BIOPHYSICS QUANTITATIVE ANALYSIS OF …

Stochastic resonance on Newman–Watts networks of Hodgkin–Huxley neurons with local periodic driving

M Ozer, M Perc, M Uzuntarla - Physics Letters A, 2009 - Elsevier
We study the phenomenon of stochastic resonance on Newman–Watts small-world
networks consisting of biophysically realistic Hodgkin–Huxley neurons with a tunable …

Stochastic differential equation models for ion channel noise in Hodgkin-Huxley neurons

JH Goldwyn, NS Imennov, M Famulare… - Physical Review E …, 2011 - APS
The random transitions of ion channels between conducting and nonconducting states
generate a source of internal fluctuations in a neuron, known as channel noise. The …

A multiscale investigation of repolarization variability and its role in cardiac arrhythmogenesis

E Pueyo, A Corrias, L Virág, N Jost, T Szél, A Varró… - Biophysical journal, 2011 - cell.com
Enhanced temporal and spatial variability in cardiac repolarization has been related to
increased arrhythmic risk both clinically and experimentally. Causes and modulators of …

Stochastic ion channel gating in dendritic neurons: morphology dependence and probabilistic synaptic activation of dendritic spikes

RC Cannon, C O'Donnell, MF Nolan - PLoS computational biology, 2010 - journals.plos.org
Neuronal activity is mediated through changes in the probability of stochastic transitions
between open and closed states of ion channels. While differences in morphology define …

Accurate and fast simulation of channel noise in conductance-based model neurons by diffusion approximation

D Linaro, M Storace, M Giugliano - PLoS computational biology, 2011 - journals.plos.org
Stochastic channel gating is the major source of intrinsic neuronal noise whose functional
consequences at the microcircuit-and network-levels have been only partly explored. A …

An exact stochastic hybrid model of excitable membranes including spatio-temporal evolution

E Buckwar, MG Riedler - Journal of mathematical biology, 2011 - Springer
In this paper, we present a mathematical description for excitable biological membranes, in
particular neuronal membranes. We aim to model the (spatio-) temporal dynamics, eg, the …

Effects of electrode-to-fiber distance on temporal neural response with electrical stimulation

H Mino, JT Rubinstein, CA Miller… - IEEE transactions on …, 2004 - ieeexplore.ieee.org
This paper presents an analysis of the effects of the electrode-to-fiber distance on the
temporal response properties of an auditory nerve fiber stimulated by electric current pulses …