Functionalized chitosan for cancer nano drug delivery

Y Zaiki, A Iskandar, TW Wong - Biotechnology Advances, 2023 - Elsevier
Chitosan is a biotechnological derivative of chitin receiving a widespread pharmaceutical
and biomedical applications. It can be used to encapsulate and deliver cancer therapeutics …

Nanoparticles for oral delivery: targeted therapy for inflammatory bowel disease

D Li, M Yang, H Xu, M Zhu, Y Zhang, C Tian… - Journal of Materials …, 2022 - pubs.rsc.org
As a group of chronic and idiopathic gastrointestinal (GI) disorders, inflammatory bowel
disease (IBD) is characterized by recurrent intestinal mucosal inflammation. Oral …

Intestinal organoids and organoids extracellular vesicles for inflammatory bowel disease treatment

H Liu, J Sun, M Wang, S Wang, J Su, C Xu - Chemical Engineering Journal, 2023 - Elsevier
Inflammatory bowel disease (IBD), a chronic inflammatory disease of the gastrointestinal
tract, is characterized by abdominal pain, diarrhea, and bloody stools, posing a serious …

Engineering nano‐and microparticles as oral delivery vehicles to promote intestinal lymphatic drug transport

YB Miao, YJ Lin, KH Chen, PK Luo… - Advanced …, 2021 - Wiley Online Library
Targeted oral delivery of a drug via the intestinal lymphatic system (ILS) has the advantages
of protecting against hepatic first‐pass metabolism of the drug and improving its …

In vitro and ex vivo models for evaluating vaginal drug delivery systems

RL Shapiro, K DeLong, F Zulfiqar, D Carter… - Advanced drug delivery …, 2022 - Elsevier
Vaginal drug delivery systems are often preferred for treating a variety of diseases and
conditions of the female reproductive tract (FRT), as delivery can be more targeted with less …

[HTML][HTML] Rational design of oral drugs targeting mucosa delivery with gut organoid platforms

T Tong, Y Qi, D Rollins, LD Bussiere, D Dhar… - Bioactive Materials, 2023 - Elsevier
Effective oral drugs and vaccines require high delivery efficiency across the gastrointestinal
epithelia and protection of medically effective payloads (ie, immunogens) against gastric …

Biological effects of polystyrene micro-and nano-plastics on human intestinal organoid-derived epithelial tissue models without and with M cells

Y Chen, AM Williams, EB Gordon, SE Rudolph… - … , Biology and Medicine, 2023 - Elsevier
Micro-and nano-plastics (MPs and NPs) released from plastics in the environment can enter
the food chain and target the human intestine. However, knowledge about the effects of …

Ferulic acid-loaded polymeric nanoparticles prepared from nano-emulsion templates facilitate internalisation across the blood–brain barrier in model membranes

L Garcia, S Palma-Florez, V Espinosa, FS Rokni… - Nanoscale, 2023 - pubs.rsc.org
A hydroxycinnamic acid derivative, namely ferulic acid (FA) has been successfully
encapsulated in polymeric nanoparticles (NPs) based on poly (lactic-co-glycolic …

Challenges and opportunities in delivering oral peptides and proteins

H Peng, J Wang, J Chen, Y Peng, X Wang… - Expert opinion on …, 2023 - Taylor & Francis
Introduction Rapid advances in bioengineering enable the use of complex proteins as
therapeutic agents to treat diseases. Compared with conventional small molecule drugs …

Intestine‐Targeted Controlled Hydrogen‐Releasing MgH2 Microcapsules for Improving the Mitochondrial Metabolism of Inflammatory Bowel Disease

H Liu, D Chen, X Yang, M Zhao, J Zhong… - Advanced Functional …, 2024 - Wiley Online Library
The development of efficient therapeutic agents with low side effects for inflammatory bowel
disease management is a longstanding challenge. Recently, hydrogen molecule (H2) is …