DNA-based communication in populations of synthetic protocells
Developing molecular communication platforms based on orthogonal communication
channels is a crucial step towards engineering artificial multicellular systems. Here, we …
channels is a crucial step towards engineering artificial multicellular systems. Here, we …
A spatially localized architecture for fast and modular DNA computing
Cells use spatial constraints to control and accelerate the flow of information in enzyme
cascades and signalling networks. Synthetic silicon-based circuitry similarly relies on spatial …
cascades and signalling networks. Synthetic silicon-based circuitry similarly relies on spatial …
Harnessing DNA nanotechnology and chemistry for applications in photonics and electronics
Many photonic and electronic devices rely on nanotechnology and nanofabrication, but DNA-
based approaches have yet to make a significant commercial impact in these fields even …
based approaches have yet to make a significant commercial impact in these fields even …
Exploiting molecular motors as nanomachines: the mechanisms of de novo and re-engineered cytoskeletal motors
NV DelRosso, ND Derr - Current opinion in biotechnology, 2017 - Elsevier
Highlights•Cytoskeletal molecular motors are profound bionanotechnological devices.•The
mechanisms of these motors enable re-purposing and re-engineering.•They also provide …
mechanisms of these motors enable re-purposing and re-engineering.•They also provide …
Toehold mediated one-step conformation-switchable “signal-on” electrochemical DNA sensing enhanced with homogeneous enzymatic amplification
S Wang, F Yang, D Jin, Q Dai, J Tu, Y Liu… - Analytical …, 2017 - ACS Publications
The development of highly sensitive and sequence-specific electrochemical DNA (E-DNA)
sensors, featuring flexible, one-step, and “signal-on” design, is a long-lasting goal. Here, we …
sensors, featuring flexible, one-step, and “signal-on” design, is a long-lasting goal. Here, we …
A Dual-Recognition Fluorescence Enzyme-Linked Immunosorbent Assay for Specific Detection of Intact Lipid Nanoparticles via a Localized Scaffolding Autocatalytic …
Y Hu, Y Cui, Z Zhang, X Zhang, X Ma, Z Qiao… - Analytical …, 2024 - ACS Publications
Lipid nanoparticles (LNPs) are emerging as one of the most promising drug delivery
systems. The long-circulating effect of intact LNPs (i-LNPs) is the key to efficacy and toxicity …
systems. The long-circulating effect of intact LNPs (i-LNPs) is the key to efficacy and toxicity …
Rapid kinetic fingerprinting of single nucleic acid molecules by a FRET-based dynamic nanosensor
K Khanna, S Mandal, AT Blanchard, M Tewari… - Biosensors and …, 2021 - Elsevier
Biofluid-derived cell-free nucleic acids such as microRNAs (miRNAs) and circulating tumor-
derived DNAs (ctDNAs) have emerged as promising disease biomarkers. Conventional …
derived DNAs (ctDNAs) have emerged as promising disease biomarkers. Conventional …
DNA-functionalized gold nanoparticles with toehold-mediated strand displacement for nucleic acid sensors
G Ghotra, BK Nguyen, JIL Chen - ACS Applied Nano Materials, 2020 - ACS Publications
We present a study of gold nanoparticles linked by DNA that undergo toehold-mediated
strand displacement for nucleic acid sensing. The factors influencing colloidal aggregation …
strand displacement for nucleic acid sensing. The factors influencing colloidal aggregation …
Controlling dynamic DNA reactions at the surface of single-walled carbon nanotube electrodes to design hybridization platforms with a specific amperometric readout
S Fortunati, I Vasini, M Giannetto, M Mattarozzi… - Analytical …, 2022 - ACS Publications
Carbon nanotube (CNT)-based electrodes are cheap, highly performing, and robust
platforms for the fabrication of electrochemical sensors. Engineering programmable DNA …
platforms for the fabrication of electrochemical sensors. Engineering programmable DNA …
Stoichiometric quantification of spatially dense assemblies with qPAINT
Quantitative PAINT (qPAINT) is a useful method for counting well-separated molecules
within nanoscale assemblies. But whether cross-reactivity in densely-packed arrangements …
within nanoscale assemblies. But whether cross-reactivity in densely-packed arrangements …