[HTML][HTML] Piceatannol, a comprehensive review of health perspectives and pharmacological aspects

HI Al-Jaber, AK Shakya, MA Al-Qudah… - Arabian Journal of …, 2024 - Elsevier
Piceatannol, a natural polyphenolic stilbenoid found in numerous fruits and vegetables such
as grapes, passionate fruit, blueberries, and white tea, is well recognized for its diverse …

E-Stilbenes: General Chemical and Biological Aspects, Potential Pharmacological Activity Based on the Nrf2 Pathway

ELSS Mendonça, JA Xavier, MBT Fragoso, MO Silva… - Pharmaceuticals, 2024 - mdpi.com
Stilbenes are phytoalexins, and their biosynthesis can occur through a natural route
(shikimate precursor) or an alternative route (in microorganism cultures). The latter is a …

[HTML][HTML] An Overview of Bioactive Compounds' Role in Modulating the Nrf2/Keap1/NF-κB Pathway to Alleviate Lipopolysaccharide-Induced Endometritis

MZ Khan, W Chen, X Liu, X Kou, A Khan… - International Journal of …, 2024 - mdpi.com
Endometritis is a common inflammatory condition of the uterine endometrial lining that
primarily affects perinatal dairy animals and causes significant economic losses in …

Hydrogen sulfide protects the endometrium in a rat model of type 1 diabetes via modulation of PPARγ/mTOR and Nrf-2/NF-κb pathways

HA Abdel-Hamid, H Marey… - Archives of physiology …, 2024 - Taylor & Francis
Diabetes is one of the leading causes of endometrial diseases in women. No study has
addressed the influence of hydrogen sulphide (H2S) donors on endometrial injury on top of …

Plant polyphenols and human health: Novel findings for future therapeutic developments

A Di Sotto, S Di Giacomo - Nutrients, 2023 - mdpi.com
Polyphenols are a large class of plant secondary metabolites that are biosynthetically
derived from the shikimate pathway and characterized by aromatic rings with one or more …

Protective effect of eicosapentaenoic acid against estradiol valerate-induced endometrial hyperplasia via modulation of NF-κB/HIF-1α/VEGF signaling pathway in rats

WY Abdelzaher, MA Ibrahim, M Hassan… - Chemico-Biological …, 2023 - Elsevier
Background Early diagnosis and treatment of endometrial hyperplasia (EH) remains
mandatory for endometrial cancer (EC) prevention. Objective To study the possible …

Therapeutic effect of oral insulin-chitosan nanobeads pectin-dextrin shell on streptozotocin-diabetic male albino rats

H Ramadan, N Moustafa, RR Ahmed, AAG El-Shahawy… - Heliyon, 2024 - cell.com
The current study inspects the therapeutic effects of orally ingested insulin-loaded chitosan
nanobeads (INS-CsNBs) with a pectin-dextrin (PD) coating on streptozotocin (STZ)-induced …

Repeated exposure to physiologically effective doses of contraceptive hormones ethinyl estradiol or levonorgestrel do not alter the reinforcing effects of a brief visual …

KR McNealy, MW Oevermann, MKL Knabel… - Hormones and …, 2024 - Elsevier
Estradiol and progesterone potentiate and attenuate reward processes, respectively.
Despite these well-characterized effects, there is minimal research on the effects of synthetic …

Self-Nanoemulsifying Drug Delivery System of 2-Methoxyestradiol Exhibits Enhanced Anti-Proliferative and Pro-Apoptotic Activities in MCF-7 Breast Cancer Cells

SD Al-Qahtani, HH Bin-Melaih, EM Atiya, UA Fahmy… - Life, 2022 - mdpi.com
(1) Background: 2-Methoxyestradiol (2ME) is a metabolite of estrogens and possesses
promising anti-proliferative and cytotoxic activities. However, it suffers unfavorable …

Современный взгляд на изучение факторов риска, приводящих к малигнизации гиперпластических процессов эндометрия: Обзор литературы

БИ Имашева, МА Камалиев, ВН Локшин… - Репродуктивная …, 2022 - repromed.kz
Аннотация Актуальность: Гиперплазия эндометрия является наиболее актуальной
проблемой в структуре гинекологических заболеваний ввиду высокой вероятности …