Hereditary amyloidogenic transthyretin (ATTRv) amyloidosis with polyneuropathy (also
known as familial amyloid polyneuropathy) is a condition with adult onset caused by …

Transthyretin (ATTR) amyloidosis is a life-threatening, gain-of-toxic-function disease
characterised by extracellular deposition of amyloid fibrils composed of transthyretin (TTR) …

ATTR amyloidosis is caused by systemic deposition of transthyretin (TTR) and comprises
ATTRwt (wt for wild-type) amyloidosis, ATTRv (v for variant) amyloidosis, and acquired ATTR …

Intracellular signaling by mitogen-activated protein (MAP) kinases (MAPK) is involved in
many cellular responses and in the regulation of various physiological and pathological …

Familial amyloidotic polyneuropathy (FAP) is an inherited autosomal dominant disease that
is commonly caused by accumulation of deposits of transthyretin (TTR) amyloid around …

Transthyretin (TTR) amyloidosis is caused by systemic deposition of wild-type or variant
amyloidogenic TTR (ATTRwt and ATTRv, respectively). ATTRwt amyloidosis has …

In the genesis of Alzheimer's disease (AD), converging lines of evidence suggest that
amyloid-β peptide (Aβ) triggers a pathogenic cascade leading to neuronal loss. It was long …

The role of innate and adaptive inflammation as a primary driver or modifier of neuropathy in
premorbidly normal nerves, and as a critical player in amplifying neuropathies of other …

Hereditary transthyretin (TTR)‐related amyloidosis (ATTRm amyloidosis) is an endemic/non‐
endemic, autosomal‐dominant, early‐and late‐onset, rare, progressive disorder …

High mobility group box 1 (HMGB1) was originally identified as ubiquitously expressed
nonhistone DNA-binding protein, but recently, it was found to act as an endogenous danger …