[HTML][HTML] Mallotus oppositifolius (Geiseler) Müll. Arg.: The first review of its botany, ethnomedicinal uses, phytochemistry and biological activities

TL Adetunji, AE Adetunji, CA Odebunmi… - South African Journal of …, 2022 - Elsevier
Mallotus oppositifolius (Geiseler) Müll. Arg.(Euphorbiaceae) is an important and
multipurpose medicinal herb found in different African countries. Its various parts possess …

Antidepressant-like effects of the leaf extract of Mallotus oppositifolius (Geiseler) Müll. Arg.(Euphorbiaceae) in the chronic unpredictable mild stress model: A role of …

B Kwofie, P Debrah, P Amoateng, DW Adongo… - Neuroscience, 2024 - Elsevier
The gut microbiota has been posited as a target for the treatment of major depressive
disorder. Herein, we investigated the effect of the hydroethanolic leaf extract of Mallotus …

Extract of Mallotus oppositifolius (Geiseler) Müll. Arg. increased prefrontal cortex dendritic spine density and serotonin and attenuated para-chlorophenylalanine …

KKE Kukuia, F Appiah, GJ Dugbartey… - Frontiers in …, 2022 - frontiersin.org
Background/Aim: Depression-related aggression is linked to serotonin (5-HT) and dendritic
spine alterations. Although Mallotus oppositifolius extract (MOE) has potential for reducing …

[HTML][HTML] Tert-butyl 4-((1-phenyl-1H-pyrazol-4-yl) methyl) piperazine-1-carboxylate (LQFM104)–new piperazine derivative with antianxiety and antidepressant-like …

DM da Silva, G Sanz, BG Vaz, FS de Carvalho… - Biomedicine & …, 2018 - Elsevier
The piperazine derivatives correspond to an extensive chemical class of compounds with
numerous neuropharmacological activities, including antidepressant (eg, nefazodone …

An extract of Synedrella nodiflora (L) Gaertn exhibits antidepressant properties through monoaminergic mechanisms

P Amoateng, KKE Kukuia, JA Mensah… - Metabolic brain …, 2018 - Springer
Synedrella nodiflora (SNE) has been used traditionally for many neurological conditions and
some of these neuroactive effects have been scientifically substantiated. The usefulness of …

Enhancement of inhibitory neurotransmission and inhibition of excitatory mechanisms underlie the anticonvulsant effects of Mallotus oppositifolius

KKE Kukuia, EO Ameyaw, E Woode… - Journal of Pharmacy …, 2016 - journals.lww.com
Aims: This study investigated the anticonvulsant properties and possible mechanism of
action of the 70% v/v hydroalcoholic extract of the leaves of M. oppositifolius. Materials and …

Antidepressant Potentials of Components from Trichilia monadelpha (Thonn.) JJ de Wilde in Murine Models

KKE Kukuia, JA Mensah, P Amoateng… - Evidence‐Based …, 2018 - Wiley Online Library
Trichilia monadelpha is a common medicinal plant used traditionally in treating central
nervous system conditions such as epilepsy, depression, pain, and psychosis. In this study …

Scientific evidence of plant with a rapid-onset and sustained antidepressant effect in a chronic model of depression: Mallotus oppositifolius

KKE Kukuia, EO Ameyaw, E Woode… - Journal of Basic and …, 2016 - degruyter.com
Background: One of the major drawbacks of current depression pharmacotherapy is the
delay in symptom improvement, aside from the untoward side effects and lack of efficacy …

Psychotropic Effects of an Alcoholic Extract from the Leaves of Albizia zygia (Leguminosae‐Mimosoideae)

P Amoateng, D Osei-Safo, KKE Kukuia… - Evidence‐Based …, 2017 - Wiley Online Library
Background. Albizia zygia is used in Ghanaian traditional medicine for the management of
mental disorders. The present study tested the hypothesis that an extract of the leaves of …

Evaluation Of Biochemical, Hematological And Antioxidant Properties In Mice Exposed To A Triherbal (Nigella sativa, Carica papaya and Boswellia sacra) Formular

S Kehinde, SM Adebayo, AL Adesiyan, EA Kade… - BioRxiv, 2020 - biorxiv.org
Nigella sativa, Carica papaya and Boswellia sacra are medicinal plants in the commonly
used in folkloric medicine due to the presence of its immense therapeutic properties. Fifty …