Protein post-translational modifications (PTMs) profoundly influence protein functions and
play crucial roles in essentially all cell biological processes. The diverse realm of PTMs and …

Transcription factors (TFs) are key regulators of intrinsic cellular processes, such as
differentiation and development, and of the cellular response to external perturbation …

Abstract SMART (Simple Modular Architecture Research Tool) is a web resource
(http://smart. embl. de) for the identification and annotation of protein domains and the …

More and more in-depth studies have revealed that the occurrence and development of
tumors depend on gene mutation and tumor heterogeneity. The most important …

Post-translational modification (PTM) of proteins allows cells to regulate protein functions,
transduce signals and respond to perturbations. PTMs expand protein functionality and …

Nuclear pore complexes are fundamental components of all eukaryotic cells that mediate
nucleocytoplasmic exchange. Determining their 110-megadalton structure imposes a …

Advancements in genomic and proteomic technologies have powered the creation of large
gene and protein networks (“interactomes”) for understanding biological systems. However …

Post‐translational modifications (PTM s) of proteins are central in any kind of cellular
signaling. Modern mass spectrometry technologies enable comprehensive identification and …

Protein post-translational modifications (PTMs) play a pivotal role in numerous biological
processes by modulating regulation of protein function. We have developed iPTMnet (http …

Cancer is often driven by the accumulation of genetic alterations, including single nucleotide
variants, small insertions or deletions, gene fusions, copy-number variations, and large …