[HTML][HTML] Salidroside as a potential neuroprotective agent for ischemic stroke: a review of sources, pharmacokinetics, mechanism and safety

F Fan, L Yang, R Li, X Zou, N Li, X Meng… - Biomedicine & …, 2020 - Elsevier
Salidroside (Sal) is a bioactive extract principally from traditional herbal medicine such as
Rhodiola rosea L., which has been commonly used for hundreds of years in Asia countries …

Therapeutic potential of matrix metalloproteinase inhibition in breast cancer

ES Radisky… - Journal of cellular …, 2017 - Wiley Online Library
Matrix metalloproteinases (MMPs) are a family of zinc endopeptidases that cleave nearly all
components of the extracellular matrix as well as many other soluble and cell‐associated …

Three-Dimensional Blood-Brain Barrier Model for in vitro Studies of Neurovascular Pathology

H Cho, JH Seo, KHK Wong, Y Terasaki, J Park… - Scientific reports, 2015 - nature.com
Blood–brain barrier (BBB) pathology leads to neurovascular disorders and is an important
target for therapies. However, the study of BBB pathology is difficult in the absence of …

[HTML][HTML] Matrix metalloproteinases as breast cancer drivers and therapeutic targets

ES Radisky, DC Radisky - Frontiers in bioscience (Landmark …, 2015 - ncbi.nlm.nih.gov
Members of the matrix metalloproteinase (MMP) family have been identified as poor
prognosis markers for breast cancer patients and as drivers of many facets of the tumor …

[HTML][HTML] TIMP1 preserves the blood–brain barrier through interacting with CD63/integrin β1 complex and regulating downstream FAK/RhoA signaling

J Tang, Y Kang, L Huang, L Wu, Y Peng - Acta Pharmaceutica Sinica B, 2020 - Elsevier
Blood–brain barrier (BBB) breakdown and the associated microvascular hyperpermeability
are hallmark features of several neurological disorders, including traumatic brain injury …

[HTML][HTML] Early passage of Toxoplasma gondii across the blood–brain barrier

EC Ross, GC Olivera, A Barragan - Trends in parasitology, 2022 - cell.com
The blood–brain barrier (BBB) efficiently protects the central nervous system (CNS) from
infectious insults. Yet, the apicomplexan parasite Toxoplasma gondii has a remarkable …

Annexin A1 restores Aβ1‐42‐induced blood–brain barrier disruption through the inhibition of RhoA‐ROCK signaling pathway

JC Park, SH Baik, SH Han, HJ Cho, H Choi, HJ Kim… - Aging cell, 2017 - Wiley Online Library
The blood–brain barrier (BBB) is composed of brain capillary endothelial cells and has an
important role in maintaining homeostasis of the brain separating the blood from the …

Unravelling the distinct biological functions and potential therapeutic applications of TIMP2 in cancer

D Peeney, Y Liu, C Lazaroff, S Gurung… - …, 2022 - academic.oup.com
Tissue inhibitors of metalloproteinases (TIMPs) are a conserved family of proteins that were
originally identified as endogenous inhibitors of matrixin and adamalysin endopeptidase …

[HTML][HTML] The neurogliovascular unit in hepatic encephalopathy

W Claeys, L Van Hoecke, S Lefere, A Geerts… - JHEP reports, 2021 - Elsevier
Hepatic encephalopathy (HE) is a neurological complication of hepatic dysfunction and
portosystemic shunting. It is highly prevalent in patients with cirrhosis and is associated with …

rpS6 regulates blood–testis barrier dynamics through Akt-mediated effects on MMP-9

KW Mok, DD Mruk, CY Cheng - Journal of cell science, 2014 - journals.biologists.com
Mammalian target of rapamycin complex 1 (mTORC1) is an emerging regulator of blood–
tissue barriers that utilizes ribosomal protein S6 (rpS6) as the downstream signaling …