Mechanochemistry: new tools to navigate the uncharted territory of “impossible” reactions
F Cuccu, L De Luca, F Delogu, E Colacino… - …, 2022 - Wiley Online Library
Mechanochemical transformations have made chemists enter unknown territories, forcing a
different chemistry perspective. While questioning or revisiting familiar concepts belonging …
different chemistry perspective. While questioning or revisiting familiar concepts belonging …
The hitchhiker's guide to flow chemistry∥
Flow chemistry involves the use of channels or tubing to conduct a reaction in a continuous
stream rather than in a flask. Flow equipment provides chemists with unique control over …
stream rather than in a flask. Flow equipment provides chemists with unique control over …
How to approach flow chemistry
Flow chemistry is a widely explored technology whose intrinsic features both facilitate and
provide reproducible access to a broad range of chemical processes that are otherwise …
provide reproducible access to a broad range of chemical processes that are otherwise …
Electrochemical dearomative dicarboxylation of heterocycles with highly negative reduction potentials
Y You, W Kanna, H Takano, H Hayashi… - Journal of the …, 2022 - ACS Publications
The dearomative dicarboxylation of stable heteroaromatics using CO2 is highly challenging
but represents a very powerful method for producing synthetically useful dicarboxylic acids …
but represents a very powerful method for producing synthetically useful dicarboxylic acids …
Taming hazardous chemistry by continuous flow technology
M Movsisyan, EIP Delbeke, J Berton… - Chemical Society …, 2016 - pubs.rsc.org
Over the last two decades, flow technologies have become increasingly popular in the field
of organic chemistry, offering solutions for engineering and/or chemical problems. Flow …
of organic chemistry, offering solutions for engineering and/or chemical problems. Flow …
Continuous flow chemistry: where are we now? Recent applications, challenges and limitations
FM Akwi, P Watts - Chemical communications, 2018 - pubs.rsc.org
A general outlook of the changing face of chemical synthesis is provided in this article
through recent applications of continuous flow processing in both industry and academia …
through recent applications of continuous flow processing in both industry and academia …
Photoredox activation of carbon dioxide for amino acid synthesis in continuous flow
Although carbon dioxide (CO2) is highly abundant, its low reactivity has limited its use in
chemical synthesis. In particular, methods for carbon–carbon bond formation generally rely …
chemical synthesis. In particular, methods for carbon–carbon bond formation generally rely …
Organic synthesis: march of the machines
SV Ley, DE Fitzpatrick, RJ Ingham… - Angewandte Chemie …, 2015 - Wiley Online Library
Organic synthesis is changing; in a world where budgets are constrained and the
environmental impacts of practice are scrutinized, it is increasingly recognized that the …
environmental impacts of practice are scrutinized, it is increasingly recognized that the …
The use of gases in flow synthesis
CJ Mallia, IR Baxendale - Organic Process Research & …, 2016 - ACS Publications
This review will highlight the potential benefits that can be leveraged by using flow chemistry
to allow gases to be used in research in a safer and more efficient way. An overview of the …
to allow gases to be used in research in a safer and more efficient way. An overview of the …
Safety assessment in development and operation of modular continuous-flow processes
N Kockmann, P Thenée, C Fleischer-Trebes… - Reaction Chemistry & …, 2017 - pubs.rsc.org
Improved safety is one of the main drivers for microreactor application in chemical process
development and small-scale production. Typical examples of hazardous chemistry are …
development and small-scale production. Typical examples of hazardous chemistry are …