Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid
haematopoiesis that form an essential interface between the innate sensing of pathogens …

Viral respiratory tract infections are associated with asthma inception in early life and asthma
exacerbations in older children and adults. Although how viruses influence asthma inception …

Asthma is a heterogeneous disease with many phenotypes, and age at disease onset is an
important factor in separating the phenotypes. Genetic factors, atopy, and early respiratory …

Respiratory viral infections are a leading cause of disease and mortality. The severity of
these illnesses can vary markedly from mild or asymptomatic upper airway infections to …

Of the chronic diseases affecting grade-school children, asthma is the most common and
accounts for the greatest number of school days missed. Moreover, it can influence family …

IFN-α/β was first described as a potent inhibitor of viral replication, but it is now appreciated
that IFN signaling plays a pleiotropic role in regulating peripheral T cell functions. Recently …

Unlike other picornaviruses, hepatitis A virus (HAV) is cloaked in host membranes when
released from cells, providing protection from neutralizing antibodies and facilitating spread …

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection is a new rapidly spreading infectious disease. Current …

Background Frequent viral lower respiratory infections in early life are an independent risk
factor for asthma onset. This risk and the development of persistent asthma are significantly …

Background Rhinovirus infections are the dominant cause of asthma exacerbations, and
deficient virus induction of IFN-α/β/λ in asthmatic patients is important in asthma …