Human dendritic cell subsets: an update
Dendritic cells (DC) are a class of bone‐marrow‐derived cells arising from lympho‐myeloid
haematopoiesis that form an essential interface between the innate sensing of pathogens …
haematopoiesis that form an essential interface between the innate sensing of pathogens …
[HTML][HTML] Viral infections in allergy and immunology: how allergic inflammation influences viral infections and illness
MR Edwards, K Strong, A Cameron, RP Walton… - Journal of Allergy and …, 2017 - Elsevier
Viral respiratory tract infections are associated with asthma inception in early life and asthma
exacerbations in older children and adults. Although how viruses influence asthma inception …
exacerbations in older children and adults. Although how viruses influence asthma inception …
Phenotypes, risk factors, and mechanisms of adult‐onset asthma
P Ilmarinen, LE Tuomisto… - Mediators of …, 2015 - Wiley Online Library
Asthma is a heterogeneous disease with many phenotypes, and age at disease onset is an
important factor in separating the phenotypes. Genetic factors, atopy, and early respiratory …
important factor in separating the phenotypes. Genetic factors, atopy, and early respiratory …
[HTML][HTML] Respiratory viral infections and host responses; insights from genomics
Respiratory viral infections are a leading cause of disease and mortality. The severity of
these illnesses can vary markedly from mild or asymptomatic upper airway infections to …
these illnesses can vary markedly from mild or asymptomatic upper airway infections to …
The contributions of allergic sensitization and respiratory pathogens to asthma inception
DJ Jackson, JE Gern, RF Lemanske Jr - Journal of Allergy and Clinical …, 2016 - Elsevier
Of the chronic diseases affecting grade-school children, asthma is the most common and
accounts for the greatest number of school days missed. Moreover, it can influence family …
accounts for the greatest number of school days missed. Moreover, it can influence family …
Interferon at the crossroads of allergy and viral infections
SR Gonzales-van Horn, JD Farrar - Journal of Leucocyte …, 2015 - academic.oup.com
IFN-α/β was first described as a potent inhibitor of viral replication, but it is now appreciated
that IFN signaling plays a pleiotropic role in regulating peripheral T cell functions. Recently …
that IFN signaling plays a pleiotropic role in regulating peripheral T cell functions. Recently …
[HTML][HTML] Human pDCs preferentially sense enveloped hepatitis A virions
Unlike other picornaviruses, hepatitis A virus (HAV) is cloaked in host membranes when
released from cells, providing protection from neutralizing antibodies and facilitating spread …
released from cells, providing protection from neutralizing antibodies and facilitating spread …
Treatment of COVID-19-exacerbated asthma: should systemic corticosteroids be used?
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection is a new rapidly spreading infectious disease. Current …
coronavirus 2 (SARS-CoV-2) infection is a new rapidly spreading infectious disease. Current …
Aeroallergen-induced IL-33 predisposes to respiratory virus–induced asthma by dampening antiviral immunity
Background Frequent viral lower respiratory infections in early life are an independent risk
factor for asthma onset. This risk and the development of persistent asthma are significantly …
factor for asthma onset. This risk and the development of persistent asthma are significantly …
[HTML][HTML] Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons
V Gielen, A Sykes, J Zhu, B Chan, J Macintyre… - Journal of Allergy and …, 2015 - Elsevier
Background Rhinovirus infections are the dominant cause of asthma exacerbations, and
deficient virus induction of IFN-α/β/λ in asthmatic patients is important in asthma …
deficient virus induction of IFN-α/β/λ in asthmatic patients is important in asthma …