Cancer is one of the leading causes of death and morbidity with a complex pathophysiology.
Traditional cancer therapies include chemotherapy, radiation therapy, targeted therapy, and …

Nanotechnology has been extensively studied and exploited for cancer treatment as
nanoparticles can play a significant role as a drug delivery system. Compared to …

Anthracyclines have been important and effective treatments against a number of cancers
since their discovery. However, their use in therapy has been complicated by severe side …

Since the beginning of pharmaceutical research, drug delivery methods have been an
integral part of it. Polymeric micelles (PMs) have emerged as multifunctional nanoparticles in …

Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are
nanosized membrane vesicles derived from most cell types. Carrying diverse biomolecules …

Recent advancements in drug delivery technologies utilizing a variety of carriers have
resulted in a path-breaking revolution in the approach towards diagnosis and therapy alike …

Tumor microenvironment (TME), which characteristically displays hypoxia,
immunosuppression, reprogramming metabolism and mild acidity, has been considered as …

Nanocarriers as drug/biomolecule delivery systems have been significantly developed
during recent decades. Given the stability, reasonable delivery efficiency, and safety of …

Exosomes are a unique subpopulation of naturally occurring extracellular vesicles which are
smaller intracellular membrane nanoparticle vesicles. Exosomes have proven to be …

Esophageal cancer (EC) is a common gastrointestinal malignancy with poor prognosis and
high mortality. Although combined therapeutic strategies have been developed, the 5-year …