Despite the plethora of empirical studies conducted to date, debate continues about whether
and to what extent results should be returned to participants of genomic research. We aimed …

Advances in genetics and genomics are transforming medical practice, resulting in a
dramatic growth of genetic testing in the health care system. The rapid development of new …

Although the integration of whole genome sequencing (WGS) into standard medical practice
is rapidly becoming feasible, physicians may be unprepared to use it. Primary care …

After two decades of genetic testing and research, the BRCA1 and BRCA2 genes are two of
the most well-characterized genes in the human genome. As a result, variants of uncertain …

Research on the use of genome and exome sequencing for diagnosis, identification of
potential therapies, precision prescribing of pharmaceuticals, and identification of disease …

Abstract Purpose The Clinical Sequencing Exploratory Research (CSER) Consortium
encompasses nine National Institutes of Health–funded U-award projects investigating …

Background While integrating genomic sequencing into clinical care carries clear medical
benefits, it also raises difficult ethical questions. Compared to traditional sequencing …

Introduction A major consideration for the implementation of a learning health system (LHS)
is consent from participants to the use of their data for research purposes. The main …

Human genomics is a translational field spanning research, clinical care, public health, and
direct-to-consumer testing. However, law differs across these domains on issues including …

A survey was conducted to assess citizens, research ethics committee members, and
researchers' attitude toward information and consent for the secondary use of health data for …