Treatment advances in EBV related lymphoproliferative diseases

K Lv, T Yin, M Yu, Z Chen, Y Zhou, F Li - Frontiers in Oncology, 2022 - frontiersin.org
Epstein Barr virus (EBV) can affect 90% of the human population. It can invade B
lymphocytes, T lymphocytes and natural killer cells of the host and remain in the host for life …

Lytic induction therapy Against Epstein–Barr virus-associated malignancies: Past, present, and future

SPT Yiu, M Dorothea, KF Hui, AKS Chiang - Cancers, 2020 - mdpi.com
Epstein–Barr virus (EBV) lytic induction therapy is an emerging virus-targeted therapeutic
approach that exploits the presence of EBV in tumor cells to confer specific killing effects …

Knockdown of EBV-encoded circRNA circRPMS1 suppresses nasopharyngeal carcinoma cell proliferation and metastasis through sponging multiple miRNAs

Q Liu, M Shuai, Y Xia - Cancer management and research, 2019 - Taylor & Francis
Background: Epstein-Barr virus (EBV)-produced non-coding RNAs, including circular RNA
(circRNA), regulate host cell gene expression and play important roles in development of …

Epstein-Barr virus infection in the development of neurological disorders

SS Soldan, PM Lieberman - Drug Discovery Today: Disease Models, 2020 - Elsevier
Epstein-Barr Virus (EBV) is a ubiquitous human herpesvirus that contributes to the etiology
of diverse human cancers and auto-immune diseases. EBV establishes a relatively benign …

Current approach and novel perspectives in nasopharyngeal carcinoma: the role of targeting proteasome dysregulation as a molecular landmark in nasopharyngeal …

R Yarza, M Bover, MT Agulló-Ortuño… - Journal of Experimental …, 2021 - Springer
Nasopharyngeal carcinoma (NPC) represents a molecularly paradigmatic tumor given the
complex diversity of environmental as well as host dependent factors that are closely …

In vitro and in vivo evidence that the switch from calcineurin to mTOR inhibitors may be a strategy for immunosuppression in Epstein–Barr virus–associated post …

CJ Thieme, M Schulz, P Wehler, M Anft, L Amini… - Kidney International, 2022 - Elsevier
Post-transplant lymphoproliferative disorder is a life-threatening complication of
immunosuppression following transplantation mediated by failure of T cells to control …

RNA-cleaving DNAzymes for accurate biosensing and gene therapy

X Gao, Y Liu, W Huo, Y Song, Y Chen, J Zhang, X Yang… - Nanoscale, 2023 - pubs.rsc.org
RNA-cleaving DNAzymes, which are single-stranded catalytic DNA, have attracted
considerable attention in bioanalysis and biomedical applications because of their high …

Contribution of Epstein–Barr Virus Lytic Proteins to Cancer Hallmarks and Implications from Other Oncoviruses

M Dorothea, J Xie, SPT Yiu, AKS Chiang - Cancers, 2023 - mdpi.com
Simple Summary Epstein–Barr virus (EBV) is a gamma-herpesvirus associated with a broad
variety of cancers. It employs two modes of viral replication, ie, latent and lytic cycles in …

The interplay between EBV and KSHV viral products and NF-κB pathway in oncogenesis

J Charostad, M Nakhaie, A Dehghani… - Infectious Agents and …, 2020 - Springer
Among the DNA tumor viruses Epstein-Barr virus (EBV) and Kaposi sarcoma herpesvirus
(KSHV), account for a considerable percentage of virus-associated cancers. Deregulation of …

Cyclin-dependent kinases and CDK inhibitors in virus-associated cancers

S Tavakolian, H Goudarzi, E Faghihloo - Infectious Agents and Cancer, 2020 - Springer
The role of several risk factors, such as pollution, consumption of alcohol, age, sex and
obesity in cancer progression is undeniable. Human malignancies are mainly characterized …