Apolipoprotein (apo) E is a 299‐residue protein which functions as a key regulator of plasma
lipid levels. Human apoE exists as three common isoforms and the parent form, apoE3 …

Apolipoprotein E (APOE) is the major cholesterol carrier in the brain, affecting various
normal cellular processes including neuronal growth, repair and remodeling of membranes …

What are lipid bodies? One of the problems in answering this apparently simple question is
that these macromolecular proteolipid assemblies can be relatively heterogeneous with …

Cardiovascular disease (CVD) is the leading cause of death globally. It is well-established
based on evidence accrued during the last three decades that high plasma concentrations …

Human apolipoprotein E (apoE) is a member of the family of soluble apolipoproteins.
Through its interaction with members of the low-density lipoprotein receptor family, apoE has …

Apolipoprotein (apo) E has a storied history as a lipid transport protein. The integral
association between cholesterol homeostasis and lipoprotein clearance from circulation are …

Increased levels of apolipoprotein B (apoB)-containing lipoproteins, such as low density
lipoproteins (LDL) and chylomicron remnants, are associated with the development of …

High density lipoprotein (HDL) possesses important anti-atherogenic properties and this
review addresses the molecular mechanisms underlying these functions. The structures and …

Humans have evolved mechanisms of efficient fat storage to survive famine, but these
mechanisms contribute to obesity in our current environment of plentiful food and reduced …

Animals have evolved mechanisms to maintain circulating nutrient levels when energy
demands exceed feeding opportunities. Mammals store most of their energy as …