Metastasis remains the greatest challenge in the clinical management of cancer. Cell motility
is a fundamental and ancient cellular behaviour that contributes to metastasis and is …

Signal Transducer and Activator of Transcription (STAT) pathway is connected upstream
with Janus kinases (JAK) family protein and capable of integrating inputs from different …

In the last two decades, an increasing amount of studies have investigated the use of
components based on carbon-(nano) materials in the engineering of neural interfaces, to …

Abstract The Signal Transducer and Activator of Transcription (STAT) family of proteins
consists of transcription factors that play a complex and essential role in the regulation of …

In the past decades, studies of the Janus kinases (JAKs) and signal transducers and
activators of transcription (STATs) signaling have uncovered highly conserved programs …

Prostate cancer is a main urological disease associated with significant morbidity and
mortality. Radical prostatectomy and radiotherapy are potentially curative for localized …

The tumor microenvironment consists of stromal cells and leukocytes that contribute to
cancer progression. Cross-talk between tumor cells and their microenvironment is facilitated …

Several components of the GH axis are involved in tumor progression, and GH-induced
intracellular signaling has been strongly associated with breast cancer susceptibility in …

The maintenance of genome integrity is essential for any organism survival and for the
inheritance of traits to offspring. To the purpose, cells have developed a complex DNA repair …

Abstract The Src-family kinases (SFKs), an intracellularly located group of non-receptor
tyrosine kinases are involved in oncogenesis. The importance of SFKs has been implicated …