High-risk corneal transplantation: recent developments and future possibilities

WJ Armitage, C Goodchild, MD Griffin, DJ Gunn… - …, 2019 - journals.lww.com
Human corneal transplantation (keratoplasty) is typically considered to have superior short-
and long-term outcomes and lower requirement for immunosuppression compared to solid …

Macrophages in transplantation: a matter of plasticity, polarization, and diversity

SE Panzer - Transplantation, 2022 - journals.lww.com
Macrophages have emerged at the forefront of research in immunology and transplantation
because of recent advances in basic science. New findings have illuminated macrophage …

Targeting the monocyte–macrophage lineage in solid organ transplantation

TPP Van den Bosch, NM Kannegieter… - Frontiers in …, 2017 - frontiersin.org
There is an unmet clinical need for immunotherapeutic strategies that specifically target the
active immune cells participating in the process of rejection after solid organ transplantation …

The evolving roles of macrophages in organ transplantation

J Li, C Li, Q Zhuang, B Peng, Y Zhu… - Journal of …, 2019 - Wiley Online Library
Organ transplantation is a life‐saving strategy for patients with end‐stage organ failure. Over
the past few decades, organ transplantation has achieved an excellent success in short …

Immunomodulatory plasticity of mesenchymal stem cells: a potential key to successful solid organ transplantation

U Kaundal, U Bagai, A Rakha - Journal of Translational Medicine, 2018 - Springer
Organ transplantation remains to be a treatment of choice for patients suffering from
irreversible organ failure. Immunosuppressive (IS) drugs employed to maintain the allograft …

Myeloid-derived suppressor cells and their potential application in transplantation

JR Scalea, YS Lee, E Davila, JS Bromberg - Transplantation, 2018 - journals.lww.com
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of
immunosuppressive cells of the myeloid lineage upregulated by mediators of inflammation …

[HTML][HTML] Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes

A Singh, S Ramachandran, ML Graham… - Nature …, 2019 - nature.com
Immune tolerance to allografts has been pursued for decades as an important goal in
transplantation. Administration of apoptotic donor splenocytes effectively induces antigen …

Aging affects the role of myeloid-derived suppressor cells in alloimmunity

A Schroeter, MJ Roesel, T Matsunaga, Y Xiao… - Frontiers in …, 2022 - frontiersin.org
Myeloid-derived suppressor cells (MDSC) are defined as a group of myeloid cells with
potent immunoregulatory functions that have been shown to be involved in a variety of …

Cell membrane bioconjugation and membrane-derived nanomaterials for immunotherapy

PY Li, Z Fan, H Cheng - Bioconjugate chemistry, 2018 - ACS Publications
Cell membrane engineering, including live cell membrane bioconjugation and cell
membrane-derived nanomaterials is a highly promising strategy to modulate immune …

Targeting age‐specific changes in CD4+ T cell metabolism ameliorates alloimmune responses and prolongs graft survival

Y Nian, J Iske, R Maenosono, K Minami… - Aging …, 2021 - Wiley Online Library
Age impacts alloimmunity. Effects of aging on T‐cell metabolism and the potential to
interfere with immunosuppressants have not been explored yet. Here, we dissected …