Inflammatory cytokines: potential biomarkers of immunologic dysfunction in autism spectrum disorders

N Xu, X Li, Y Zhong - Mediators of inflammation, 2015 - Wiley Online Library
Autism is a disorder of neurobiological origin characterized by problems in communication
and social skills and repetitive behavior. After more than six decades of research, the …

Biomarkers in autism spectrum disorders: Current progress

L Shen, XK Liu, H Zhang, J Lin, C Feng, J Iqbal - Clinica Chimica Acta, 2020 - Elsevier
Autism spectrum disorder (ASD) refers to a group of complex neurodevelopmental disorders
characterized by social interaction and communication deficits and repetitive and …

Impaired carbohydrate digestion and transport and mucosal dysbiosis in the intestines of children with autism and gastrointestinal disturbances

BL Williams, M Hornig, T Buie, ML Bauman… - PloS one, 2011 - journals.plos.org
Gastrointestinal disturbances are commonly reported in children with autism, complicate
clinical management, and may contribute to behavioral impairment. Reports of deficiencies …

The neurobiology of autism spectrum disorders

M Parellada, MJ Penzol, L Pina, C Moreno… - European …, 2014 - cambridge.org
Data is progressively and robustly accumulating regarding the biological basis of autism.
Autism spectrum disorders (ASD) are currently considered a group of neurodevelopmental …

A decade from discovery to therapy: Lingo-1, the dark horse in neurological and psychiatric disorders

JL Andrews, F Fernandez-Enright - Neuroscience & Biobehavioral …, 2015 - Elsevier
Leucine-rich repeat and immunoglobulin domain-containing protein (Lingo-1) is a potent
negative regulator of neuron and oligodendrocyte survival, neurite extension, axon …

Novel contribution of secreted amyloid-β precursor protein to white matter brain enlargement in autism spectrum disorder

DK Sokol, B Maloney, CJ Westmark… - Frontiers in psychiatry, 2019 - frontiersin.org
The most replicated neuroanatomical finding in autism is the tendency toward brain
overgrowth, especially in younger children. Research shows that both gray and white matter …

Serum and cerebrospinal fluid immune mediators in children with autistic disorder: a longitudinal study

CA Pardo, CA Farmer, A Thurm, FM Shebl, J Ilieva… - Molecular Autism, 2017 - Springer
Background The causes of autism likely involve genetic and environmental factors that
influence neurobiological changes and the neurological and behavioral features of the …

Neuron–glia interactions in tuberous sclerosis complex affect the synaptic balance in 2D and organoid cultures

S Dooves, AJH van Velthoven, LG Suciati, VM Heine - Cells, 2021 - mdpi.com
Tuberous sclerosis complex (TSC) is a genetic disease affecting the brain. Neurological
symptoms like epilepsy and neurodevelopmental issues cause a significant burden on …

Increased epidermal growth factor receptor (EGFR) associated with hepatocyte growth factor (HGF) and symptom severity in children with autism spectrum disorders …

AJ Russo - Journal of Central Nervous System Disease, 2014 - journals.sagepub.com
Background One in 88 children in the US is thought to have one of the autism spectrum
disorders (ASDs). ASDs are characterized by social impairments and communication …

Increased serum EGF but not SDF-1 levels are associated with the pathophysiology and development of generalized anxiety disorder

ASM Roknuzzaman, MMAS Qusar, M Shahriar… - Scientific Reports, 2024 - nature.com
Generalized anxiety disorder (GAD) is a common and persistent mental illness
accompanied by uncontrollable worries for daily staff. Physiological, environmental, genetic …