Wilms tumour (WT) is a childhood embryonal tumour that is paradigmatic of the intersection
between disrupted organogenesis and tumorigenesis. Many WT genes play a critical (non …

Dexrazoxane for preventing or reducing cardiotoxicity in adults and children with cancer
receiving anthracyclines - de Baat, EC - 2022 | Cochrane Library Skip to Content Cookies Our …

Messenger RNA encodes cellular function and phenotype. In the context of human cancer, it
defines the identities of malignant cells and the diversity of tumor tissue. We studied 72,501 …

Abstract The Renal Tumour Study Group of the International Society of Paediatric Oncology
(SIOP–RTSG) has developed a new protocol for the diagnosis and treatment of childhood …

On the basis of the results of previous national and international trials and studies, the Renal
Tumour Study Group of the International Society of Paediatric Oncology (SIOP–RTSG) has …

Wilms tumour is the most common renal malignancy of childhood. The disease is curable in
the majority of cases, albeit at considerable cost in terms of late treatment-related effects in …

Background Rhabdomyosarcoma is an aggressive tumour that can develop in almost any
part of the body. Doxorubicin is an effective drug against rhabdomyosarcoma, but its role in …

In Europe, almost 1000 children are diagnosed with a malignant renal tumour each year.
The vast majority of cases are nephroblastoma, also known as Wilms' tumour (WT). Most …

Background Cisplatin-based concurrent chemoradiotherapy is currently considered to be
the standard treatment regimen for patients with advanced nasopharyngeal carcinoma, but …

Survivors of childhood cancer are at risk of anthracycline-induced cardiotoxicity, which might
be prevented by dexrazoxane. However, concerns exist about the safety of dexrazoxane …