Models and mechanisms of vascular dementia

P Venkat, M Chopp, J Chen - Experimental neurology, 2015 - Elsevier
Vascular dementia (VaD) is the second leading form of dementia after Alzheimer's disease
(AD) plaguing the elderly population. VaD is a progressive disease caused by reduced …

Cardiovascular risk factors promote brain hypoperfusion leading to cognitive decline and dementia

JC de La Torre - Cardiovascular psychiatry and neurology, 2012 - Wiley Online Library
Heart disease is the major leading cause of death and disability in the world. Mainly
affecting the elderly population, heart disease and its main outcome, cardiovascular …

15-year longitudinal study of blood pressure and dementia

I Skoog, L Nilsson, G Persson, B Lernfelt, S Landahl… - The Lancet, 1996 - Elsevier
Background Vascular causes of dementia may be more common than supposed. Vascular
factors may also have a role in late-onset Alzheimer's disease, but the role of hypertension …

The age-dependent relation of blood pressure to cognitive function and dementia

C Qiu, B Winblad, L Fratiglioni - The Lancet Neurology, 2005 - thelancet.com
The relation of blood pressure with cognitive function and dementia has, in recent years,
received much attention from epidemiological research. Some cross-sectional studies have …

Subcortical ischaemic vascular dementia

GC Román, T Erkinjuntti, A Wallin, L Pantoni… - The Lancet …, 2002 - thelancet.com
Vascular dementia is the second most common type of dementia. The subcortical ischaemic
form (SIVD) frequently causes cognitive impairment and dementia in elderly people. SIVD …

Essential hypertension

FH Messerli, B Williams, E Ritz - The Lancet, 2007 - thelancet.com
Essential hypertension can be defined as a rise in blood pressure of unknown cause that
increases risk for cerebral, cardiac, and renal events. In industrialised countries, the risk of …

Midlife blood pressure and dementia: the Honolulu–Asia aging study☆

LJ Launer, GW Ross, H Petrovitch, K Masaki… - Neurobiology of …, 2000 - Elsevier
We studied the association of mid-life blood pressure to late age dementia, specifically
Alzheimer's disease and vascular dementia. Data are from the cohort of 3703 Japanese …

Cardiovascular risk factors and cognitive decline in middle-aged adults

D Knopman, LL Boland, T Mosley, G Howard, D Liao… - Neurology, 2001 - AAN Enterprises
Objective: To perform serial neuropsychological assessments to detect vascular risk factors
for cognitive decline in the Atherosclerosis Risk in Communities cohort, a large biracial …

The Mayo Clinic Study of Aging: design and sampling, participation, baseline measures and sample characteristics

RO Roberts, YE Geda, DS Knopman, RH Cha… - …, 2008 - karger.com
Background: The objective of this study was to establish a prospective population-based
cohort to investigate the prevalence, incidence and risk factors for mild cognitive impairment …

Predictors of cognitive decline and mortality of aged people over a 10-year period

RS Tilvis, MH Kähönen-Väre… - The Journals of …, 2004 - academic.oup.com
Background. The search for preventable and remediable risk conditions of cognitive decline
is ongoing, but results have thus far been inconsistent. According to the hypothesis of our 10 …