The synapse is the focus of experimental research and theory on the cellular mechanisms of
nervous system plasticity and learning, but recent research is expanding the consideration …

With advances in neonatal care, preterm neonates are surviving with an evolving
constellation of motor and cognitive disabilities that appear to be related to widespread …

Adult oligodendrocyte precursor cells (OPCs) make up around 5–8% of the glial cell
population in the CNS. Their function in the undamaged CNS is largely unknown, but their …

Functional and molecular analysis of glial voltage-and ligand-gated ion channels underwent
tremendous boost over the last 15 years. The traditional image of the glial cell as a passive …

The inwardly rectifying K+ channel Kir4. 1 is broadly expressed by CNS glia and deficits in
Kir4. 1 lead to seizures and myelin vacuolization. However, the role of oligodendrocyte Kir4 …

During brain ontogenesis, the temporal and spatial generation of the different types of
neuronal and glial cells from precursors occurs as a sequence of successive progenitor …

Programmed cell death or apoptosis is broadly responsible for the normal homeostatic
removal of cells and has been increasingly implicated in mediating pathological cell loss in …

Injury to the preterm brain has a particular predilection for cerebral white matter. White
matter injury (WMI) is the most common cause of brain injury in preterm infants and a major …

To understand the cellular and in vivo functions of specific K+ channels in glia, we have
studied mice with a null mutation in the weakly inwardly rectifying K+ channel subunit Kir4 …

Cells that express the NG2 proteoglycan are the largest proliferative progenitor population in
the postnatal central nervous system (CNS). Although this entire population has long been …