This study reports the synthesis of new 2H-chromene or coumarin based acylhydrazones,
which were evaluated for their in vitro antimycobacterial activity against reference strain …

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, which has
high levels of mortality worldwide and has already gained resistance to first-and second-line …

A series of novel dihydropyrimidine derivatives bearing an imidazole nucleus at C-4 position
were synthesized in excellent yields via Biginelli multi-component reaction. The newly …

Among the chemometric tools used in rational drug design, we find artificial neural network
methods (ANNs), a statistical learning algorithm similar to the human brain, to be quite …

Aminoethyl substituted 2-endo-fenchol prepared from (−)-fenchone was used as scaffold for
the synthesis of series of 31 amide structures by N-acylation applying cinnamic acids and …

Background: The pyrazole structure is an important heterocyclic structure and plays critical
roles in agriculture, industrial and medicine. Furthermore, compounds containing pyrazole …

Tuberculosis (TB) is an infectious diseases responsible for thousands of deaths worldwide.
Due to the use of antimycobacterial drugs, TB prevalence seemed to be controlled, but with …

A systematized review of reviews and monographs published in 2012–2013 on all aspects
of heterocyclic chemistry is given.

Tuberculosis (TB) is one the most prevalent endemic lung infection caused by the pathogen
Mycobacterium tuberculosis (Mtb). In spite of the availability of various combinations of …

Present work describe the synthesis of a new series of (Z)-3-(4-(benzo [d] thiazol-2-ylthio)
phenyl)-5-benzylidene-2-(pyridine-4-yl) thiazolidine-4-one (4a-j) from 3-(4-(benzo [d] thiazol …