The role of hippocampal replay in memory and planning
The mammalian hippocampus is important for normal memory function, particularly memory
for places and events. Place cells, neurons within the hippocampus that have spatial …
for places and events. Place cells, neurons within the hippocampus that have spatial …
Causes and consequences of representational drift
Highlights•Experimental advances allow us to see long-term drift in neural
representations.•Drift challenges classical notions of receptive fields and engrams.•Drift is …
representations.•Drift challenges classical notions of receptive fields and engrams.•Drift is …
A dedicated population for reward coding in the hippocampus
JL Gauthier, DW Tank - Neuron, 2018 - cell.com
The hippocampus plays a critical role in goal-directed navigation. Across different
environments, however, hippocampal maps are randomized, making it unclear how goal …
environments, however, hippocampal maps are randomized, making it unclear how goal …
Preconfigured dynamics in the hippocampus are guided by embryonic birthdate and rate of neurogenesis
The incorporation of new information into the hippocampal network is likely to be
constrained by its innate architecture and internally generated activity patterns. However, the …
constrained by its innate architecture and internally generated activity patterns. However, the …
Parallel emergence of stable and dynamic memory engrams in the hippocampus
T Hainmueller, M Bartos - Nature, 2018 - nature.com
During our daily life, we depend on memories of past experiences to plan future behaviour.
These memories are represented by the activity of specific neuronal groups or 'engrams' …
These memories are represented by the activity of specific neuronal groups or 'engrams' …
Reactivation predicts the consolidation of unbiased long-term cognitive maps
Spatial memories that can last a lifetime are thought to be encoded during 'online'periods of
exploration and subsequently consolidated into stable cognitive maps through their …
exploration and subsequently consolidated into stable cognitive maps through their …
How development sculpts hippocampal circuits and function
R Cossart, R Khazipov - Physiological Reviews, 2022 - journals.physiology.org
In mammals, the selective transformation of transient experience into stored memory occurs
in the hippocampus, which develops representations of specific events in the context in …
in the hippocampus, which develops representations of specific events in the context in …
Adaptive responses of neuronal mitochondria to bioenergetic challenges: Roles in neuroplasticity and disease resistance
SM Raefsky, MP Mattson - Free Radical Biology and Medicine, 2017 - Elsevier
An important concept in neurobiology is “neurons that fire together, wire together” which
means that the formation and maintenance of synapses is promoted by activation of those …
means that the formation and maintenance of synapses is promoted by activation of those …
Inhibitory control of sharp-wave ripple duration during learning in hippocampal recurrent networks
B Vancura, T Geiller, A Grosmark, V Zhao… - Nature …, 2023 - nature.com
Recurrent excitatory connections in hippocampal regions CA3 and CA2 are thought to play
a key role in the generation of sharp-wave ripples (SWRs), electrophysiological oscillations …
a key role in the generation of sharp-wave ripples (SWRs), electrophysiological oscillations …
Orchestrated ensemble activities constitute a hippocampal memory engram
The brain stores and recalls memories through a set of neurons, termed engram cells.
However, it is unclear how these cells are organized to constitute a corresponding memory …
However, it is unclear how these cells are organized to constitute a corresponding memory …