Non-traumatic intracerebral hemorrhage (ICH) is associated with a significant global burden
of disease, and despite being proportionally less frequent than ischemic stroke, in 2010 it …

Importance Recently, 6 randomized clinical trials—RESCUE-Japan-LIMIT (Recovery by
Endovascular Salvage for Cerebral Ultra-Acute Embolism—Japan Large Ischemic Core …

Objective To compare how 3 common representations (ordinal vs dichotomized as 0–1/2–6
or 0–2/3–6) of the modified Rankin Scale (mRS)—a commonly used trial outcome measure …

Background Limited evidence is available on the clinical impact of artificial intelligence (AI)
in radiology. Early health technology assessment (HTA) is a methodology to assess the …

Background and Objectives To determine the impact of endovascular therapy for large
vessel occlusion stroke in patients with vs those without premorbid disability. Methods We …

Importance The utility-weighted modified Rankin Scale (UW-mRS) has been proposed as a
patient-centered alternative primary outcome for stroke clinical trials. However, to date, there …

Introduction The Modified Rankin Scale (mRS) is the most common tool to quantify post-
stroke disability in everyday practice and by certified raters in clinical trials. However …

Data on the Likert scale are ubiquitous in medical research, including randomized trials.
Statistical analysis of such data may be conducted using the means of raw scores or the …

Importance Clinical trials have suggested that prehospital management in a mobile stroke
unit (MSU) improves functional outcomes in patients with acute ischemic stroke who are …

The main objectives of therapeutic trials in venous thromboembolism (VTE) are to prevent
recurrent VTE, major bleeding and death. While these outcomes are indeed highly relevant …