Cytokines produced by T helper cells (T h cells) have essential roles in the body's defense
against viruses. Type 1 T helper (Th1) cells are essential for the host defense toward …

Nuclear Factor-kappa B (NF-κB) is a transcription factor family that regulates a large number
of genes that are involved in important physiological processes, including survival …

Autism is a neurodevelopmental disorder characterized by stereotypic repetitive behaviors,
impaired social interactions, and communication deficits. Numerous immune system …

Helminth infections represent a significant public health concern resulting in devastating
morbidity and economic consequences across the globe. Helminths migrate through …

The ability of CD4+ T cells to differentiate into effector subsets underpins their ability to
shape the immune response and mediate host protection. During T cell receptor-induced …

Helminths, including nematodes, cestodes and trematodes, are complex parasitic organisms
that infect at least one billion people globally living in extreme poverty. Helminthic infections …

Type 2 inflammation is a defining feature of infection with parasitic worms (helminths), as
well as being responsible for widespread suffering in allergies. However, the precise …

Blastocystis is a species complex that exhibits extensive genetic diversity, evidenced by its
classification into several genetically distinct subtypes (ST). Although several studies have …

Inflammatory bowel disease and allergic asthma, as typical immune-mediated inflammatory
diseases (IMIDs), are associated with immune imbalance caused by complex interactions …

The dendritic cell signals required for the in vivo priming of IL-4–producing T cells are
unknown. We used RNA sequencing to characterize DCs from skin LN of mice exposed to …