Liquid‐assisted grinding mechanochemistry in the synthesis of pharmaceuticals
P Ying, J Yu, W Su - Advanced Synthesis & Catalysis, 2021 - Wiley Online Library
Mechanochemical reactions by milling, grinding or other types of mechanical action have
emerged as a salient green approach because of its wide applications towards academic …
emerged as a salient green approach because of its wide applications towards academic …
[HTML][HTML] Recent advances in the pharmacological diversification of quinazoline/quinazolinone hybrids
Due to the pharmacological activities of quinazoline and quinazolinone scaffolds, it has
aroused great interest in medicinal chemists for the development of new drugs or drug …
aroused great interest in medicinal chemists for the development of new drugs or drug …
Isoxazole ring as a useful scaffold in a search for new therapeutic agents
A Sysak, B Obmińska-Mrukowicz - European journal of medicinal chemistry, 2017 - Elsevier
Due to its relatively easy synthesis, isoxazole ring has been as an object of interest for
chemists and pharmacologists from research groups all over the world. Its chemical …
chemists and pharmacologists from research groups all over the world. Its chemical …
Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids
A Hybrid drug which comprises the incorporation of two drug pharmacophores in one single
molecule are basically designed to interact with multiple targets or to amplify its effect …
molecule are basically designed to interact with multiple targets or to amplify its effect …
[HTML][HTML] The synthetic and therapeutic expedition of isoxazole and its analogs
Isoxazole, constituting an important family of five-membered heterocycles with one oxygen
atom and one nitrogen atom at adjacent positions is of immense importance because of its …
atom and one nitrogen atom at adjacent positions is of immense importance because of its …
Oxazole and isoxazole: From one-pot synthesis to medical applications
N, O-containing five-membered heterocycles especially oxazole and isoxazole, have widely
been found in many natural products and drugs with relevant medicinal and pharmaceutical …
been found in many natural products and drugs with relevant medicinal and pharmaceutical …
Isoxazoline containing natural products as anticancer agents: A review
Isoxazolines are an important class of nitrogen and oxygen containing heterocycles that
belong to the azoles family which have gained much importance in the field of medicinal …
belong to the azoles family which have gained much importance in the field of medicinal …
[HTML][HTML] Recent advances in the natural products-based lead discovery for new agrochemicals
P Zhang, CB Duan, B Jin, AS Ali, X Han, H Zhang… - Advanced …, 2023 - Elsevier
Crops will be harmed by fungi, pests and weeds during their growth. In the past half century,
scientists have conducted in-depth research on natural products extracted from …
scientists have conducted in-depth research on natural products extracted from …
Advances in the development of hybrid anticancer drugs
Introduction: Hybrid anticancer drugs are of great therapeutic interests as they can
potentially overcome most of the pharmacokinetic drawbacks encountered when using …
potentially overcome most of the pharmacokinetic drawbacks encountered when using …
2‐Isoxazolines: A synthetic and medicinal overview
Isoxazolines are nitrogen‐and oxygen‐containing five‐membered heterocyclic scaffolds
with extensive biological activities. This framework can be readily obtained in good to …
with extensive biological activities. This framework can be readily obtained in good to …