Horizontal gene transfer and adaptive evolution in bacteria
Horizontal gene transfer (HGT) is arguably the most conspicuous feature of bacterial
evolution. Evidence for HGT is found in most bacterial genomes. Although HGT can …
evolution. Evidence for HGT is found in most bacterial genomes. Although HGT can …
Mobile genetic element flexibility as an underlying principle to bacterial evolution
AJ Weisberg, JH Chang - Annual Review of Microbiology, 2023 - annualreviews.org
Mobile genetic elements are key to the evolution of bacteria and traits that affect host and
ecosystem health. Here, we use a framework of a hierarchical and modular system that …
ecosystem health. Here, we use a framework of a hierarchical and modular system that …
Assembling the perfect bacterial genome using Oxford Nanopore and Illumina sequencing
A perfect bacterial genome assembly is one where the assembled sequence is an exact
match for the organism's genome—each replicon sequence is complete and contains no …
match for the organism's genome—each replicon sequence is complete and contains no …
Uncovering Listeria monocytogenes hypervirulence by harnessing its biodiversity
MM Maury, YH Tsai, C Charlier, M Touchon… - Nature …, 2016 - nature.com
Microbial pathogenesis studies are typically performed with reference strains, thereby
overlooking within-species heterogeneity in microbial virulence. Here we integrated human …
overlooking within-species heterogeneity in microbial virulence. Here we integrated human …
The impact of insertion sequences on bacterial genome plasticity and adaptability
J Vandecraen, M Chandler, A Aertsen… - Critical reviews in …, 2017 - Taylor & Francis
Transposable elements (TE), small mobile genetic elements unable to exist independently
of the host genome, were initially believed to be exclusively deleterious genomic parasites …
of the host genome, were initially believed to be exclusively deleterious genomic parasites …
Bacterial insertion sequences: their genomic impact and diversity
P Siguier, E Gourbeyre… - FEMS microbiology …, 2014 - academic.oup.com
Insertion sequences (ISs), arguably the smallest and most numerous autonomous
transposable elements (TEs), are important players in shaping their host genomes. This …
transposable elements (TEs), are important players in shaping their host genomes. This …
Invasive non-typhoidal salmonella disease: an emerging and neglected tropical disease in Africa
Invasive strains of non-typhoidal salmonellae have emerged as a prominent cause of
bloodstream infection in African adults and children, with an associated case fatality of 20 …
bloodstream infection in African adults and children, with an associated case fatality of 20 …
Aminoglycoside modifying enzymes
MS Ramirez, ME Tolmasky - Drug resistance updates, 2010 - Elsevier
Aminoglycosides have been an essential component of the armamentarium in the treatment
of life-threatening infections. Unfortunately, their efficacy has been reduced by the surge and …
of life-threatening infections. Unfortunately, their efficacy has been reduced by the surge and …
A systematic assessment of current genome-scale metabolic reconstruction tools
Background Several genome-scale metabolic reconstruction software platforms have been
developed and are being continuously updated. These tools have been widely applied to …
developed and are being continuously updated. These tools have been widely applied to …
[HTML][HTML] Bordetella pertussis pathogenesis: current and future challenges
JA Melvin, EV Scheller, JF Miller… - Nature Reviews …, 2014 - nature.com
Pertussis, also known as whooping cough, has recently re-emerged as a major public health
threat despite high levels of vaccination against the aetiological agent Bordetella pertussis …
threat despite high levels of vaccination against the aetiological agent Bordetella pertussis …