[HTML][HTML] Presence, Mode of Action, and Application of Pathway Specific Transcription Factors in Aspergillus Biosynthetic Gene Clusters

W Wang, Y Yu, NP Keller, P Wang - International Journal of Molecular …, 2021 - mdpi.com
Fungal secondary metabolites are renowned toxins as well as valuable sources of
antibiotics, cholesterol-lowering drugs, and immunosuppressants; hence, great efforts were …

An update of a green pesticide: Metarhizium anisopliae

ZY Peng, ST Huang, JT Chen, N Li, Y Wei, A Nawaz… - All Life, 2022 - Taylor & Francis
Metarhizium anisopliae (Hypocreales: Clavicipitaceae, M. anisopliae), as an invertebrate
fungal pathogen, has played a significant role in the control of many agricultural pests and …

Dual role of endophytic entomopathogenic fungi: induce plant growth and control tomato leafminer Phthorimaea absoluta

Y Zheng, Y Liu, J Zhang, X Liu, Z Ju… - Pest Management …, 2023 - Wiley Online Library
BACKGROUND Entomopathogenic fungi (EPF) are multifunctional microorganisms acting
not only as biopesticides against insect pests but also as endophytes which regulate plant …

A genomic journey in the secondary metabolite diversity of fungal plant and insect pathogens: From functional to population genomics

E Kuhnert, J Collemare - Current Opinion in Microbiology, 2022 - Elsevier
Highlights•Pathogenic fungi produce secondary metabolites (SMs) to control the host and its
environment.•Functional genomics facilitates identification of new SM effectors.•Population …

[HTML][HTML] Metabolite profiling and transcriptomic analyses demonstrate the effects of biocontrol agents on alkaloid accumulation in Fritillaria thunbergii

X Cheng, D Li, Z Jiang, C Qu, H Yan, Q Wu - BMC Plant Biology, 2023 - Springer
Abstract Background During Fritillaria thunbergii planting, pests and diseases usually
invade the plant, resulting in reduced yield and quality. Previous studies have demonstrated …

Hosts engineering and in vitro enzymatic synthesis for the discovery of novel natural products and their derivatives

H Zhang, L Guo, Y Su, R Wang, W Yang… - Critical Reviews in …, 2023 - Taylor & Francis
Novel natural products (NPs) and their derivatives are important sources for drug discovery,
which have been broadly applied in the fields of agriculture, livestock, and medicine, making …

[HTML][HTML] Discovery and heterologous biosynthesis of glycosylated polyketide luteodienoside A reveals unprecedented glucinol-mediated product offloading by a …

AA Arishi, Z Shang, E Lacey, A Crombie, D Vuong… - Chemical …, 2024 - pubs.rsc.org
Luteodienoside A is a novel glycosylated polyketide produced by the Australian fungus
Aspergillus luteorubrus MST-FP2246, consisting of an unusual 1-O-β-D-glucopyranosyl-myo …

[HTML][HTML] Scaffold repositioning of spiro-acridine derivatives as fungi chitinase inhibitor by target fishing and in vitro studies

J de Oliveira Viana, E Silva e Souza, N Sbaraini… - Scientific Reports, 2023 - nature.com
The concept of “one target, one drug, one disease” is not always true, as compounds with
previously described therapeutic applications can be useful to treat other maladies. For …

Intra-hemocoel injection of pseurotin A from Metarhizium anisopliae, induces dose-dependent reversible paralysis in the Greater Wax Moth (Galleria mellonella)

N Sbaraini, CS Phan, ES e Souza, APA Perin… - Fungal Genetics and …, 2022 - Elsevier
Species from the Metarhizium genus are the causal agents of the green muscardine disease
of insects. These fungi have been successfully employed for the biological control of pests …

Next generation AMA1-based plasmids for enhanced heterologous expression in filamentous fungi

I Roux, C Woodcraft, N Sbaraini, A Pepper, E Wong… - bioRxiv, 2024 - biorxiv.org
Episomal AMA1-based plasmids are increasingly used for expressing biosynthetic pathways
and CRISPR/Cas systems in filamentous fungi cell factories due to their high transformation …