Laboratory investigation and diagnosis of thrombotic thrombocytopenic purpura

K Dimopoulos, A Tripodi, JP Goetze - Critical Reviews in Clinical …, 2023 - Taylor & Francis
Thrombotic thrombocytopenic purpura (TTP) is a rare and potentially fatal disease for which
rapid diagnosis is crucial for patient outcomes. Deficient activity (< 10%) of the liver enzyme …

[HTML][HTML] Molecular Diagnosis Is Vital to the Accurate Classification and Management of Thrombotic Thrombocytopenic Purpura in Children

CL Karsenty, SE Kirk, HL Helber, JM Esquilin… - Frontiers in …, 2022 - frontiersin.org
Thrombotic thrombocytopenic purpura (TTP) is a rare but potentially life-threatening
hematologic disease, presenting a myriad of diagnostic and management challenges in …

[HTML][HTML] Application of PLASMIC score in risk prediction of thrombotic thrombocytopenic purpura: real-world experience from a tertiary medical center in Taiwan

CH Lee, YC Huang, SS Li, YT Hsu, YP Chen… - Frontiers in …, 2022 - frontiersin.org
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening disorder caused by severe
ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeats …

Clinical features and neurological outcomes in pediatric immune‐mediated thrombotic thrombocytopenic purpura: A report from a large pediatric hematology center

S Graciaa, S Adeagbo, G Fong, M Rollins… - Pediatric Blood & …, 2022 - Wiley Online Library
Background Thrombotic thrombocytopenic purpura (TTP) is a potentially life‐threatening
disorder characterized by microangiopathic hemolytic anemia, thrombocytopenia, and …

Challenges in the diagnosis of thrombotic thrombocytopenic purpura

RC Siniard, R Gangaraju, JE May… - Expert Review of …, 2023 - Taylor & Francis
ABSTRACT Introduction Immune-mediated TTP (iTTP) is a rare condition without
pathognomonic signs and symptoms. For this reason, the diagnosis of iTTP may be delayed …

[HTML][HTML] Pathological Mechanisms and Novel Testing Methods in Thrombotic Thrombocytopenic Purpura

HH Dolin, RW Maitta - Biomedicines, 2024 - mdpi.com
Thrombotic thrombocytopenic purpura (TTP) is an uncommon, but potentially disabling or
even deadly, thrombotic microangiopathy with a well-studied mechanism of ADAMTS13 …

Potential modifications of the PLASMIC scoring system for predicting thrombotic thrombocytopenic purpura: Sometimes, less is more

B Orhan, V Özkocaman, Ç Akdemir… - International Journal …, 2023 - Wiley Online Library
Introduction Thrombotic thrombocytopenic purpura (TTP) is a life‐threatening occlusive
disease of the microcirculation characterized by systemic platelet plugs, organ ischemia …

[HTML][HTML] Immune Thrombotic Thrombocytopenic Purpura in Elderly Patients: The Roles of PLASMIC and French Scores

M Baysal, F Hindilerden, EG Ümit… - Turkish Journal of …, 2023 - ncbi.nlm.nih.gov
Objective: In recent years, new developments have been incorporated into daily practice in
the management of immune thrombotic thrombocytopenic purpura (iTTP). In particular …

[PDF][PDF] Turk J Hematol Immune Thrombotic Thrombocytopenic Purpura in Elderly Patients; the Role for PLASMIC and French Scores Baysal et al. Immune Thrombotic …

M Baysal, F Hindilerden, EG Ümit, AM Demir… - 2023 - jag.journalagent.com
The median age of onset for iTTP is 40 years (8, 13). It has been reported that elderly iTTP
patients may present with a higher frequency of renal and neurological manifestations and …