Genetically encoded biosensors for microbial synthetic biology: from conceptual frameworks to practical applications

W Yu, X Xu, K Jin, Y Liu, J Li, G Du, X Lv, L Liu - Biotechnology Advances, 2023 - Elsevier
Genetically encoded biosensors are the vital components of synthetic biology and metabolic
engineering, as they are regarded as powerful devices for the dynamic control of genotype …

Biosystem design of Corynebacterium glutamicum for bioproduction

J Zha, Z Zhao, Z Xiao, T Eng, A Mukhopadhyay… - Current Opinion in …, 2023 - Elsevier
Highlights•Corynebacterium glutamicum has been used for many applications beyond
amino acids.•Economical, high-quality genome assemblies foster development of non-type …

Accelerating the design of pili-enabled living materials using an integrative technological workflow

Y Huang, Y Wu, H Hu, B Tong, J Wang… - Nature Chemical …, 2024 - nature.com
Bacteria can be programmed to create engineered living materials (ELMs) with self-healing
and evolvable functionalities. However, further development of ELMs is greatly hampered by …

Advances in engineering and optimization of transcription factor-based biosensors for plug-and-play small molecule detection

C Pham, PJ Stogios, A Savchenko… - Current Opinion in …, 2022 - Elsevier
Highlights•Transcription factor-based biosensors are powerful analytical synthetic biology
tools.•Biosensors can be used for detection, metabolic engineering, and protein …

A synthetic biosensor for detecting putrescine in beef samples

AS Selim, JM Perry, MA Nasr… - ACS Applied Bio …, 2022 - ACS Publications
Biogenic amines (BAs) are toxicological risks present in many food products. Putrescine is
the most common foodborne BA and is frequently used as a quality control marker …

Modulating sensitivity of an erythromycin biosensor for precise high-throughput screening of strains with different characteristics

Y Wang, S Li, N Xue, L Wang, X Zhang… - ACS Synthetic …, 2023 - ACS Publications
Genetically encoded biosensors are powerful tools for product-driven high-throughput
screening in synthetic biology and metabolic engineering. However, most biosensors can …

[HTML][HTML] Biosensor-based therapy powered by synthetic biology

C Wang, HS Zeng, KX Liu, YN Lin, H Yang… - Smart Materials in …, 2023 - Elsevier
The study of synthetic biology focusing on biosensor systems has resulted from a growing
interest in developing customized biological devices with desired cellular functions …

Construction and Application of a High-Throughput In Vivo Screening Platform for the Evolution of Nitrile Metabolism-Related Enzymes Based on a Desensitized …

L Han, X Liu, Z Cheng, W Cui, J Guo, J Yin… - ACS Synthetic …, 2022 - ACS Publications
Transcription factor (TF)-based biosensors are expected to serve as powerful tools for the
high-throughput screening of biocatalytic systems; however, most of them respond to ligands …

[HTML][HTML] Relieving metabolic burden to improve robustness and bioproduction by industrial microorganisms

J Mao, H Zhang, Y Chen, L Wei, J Liu, J Nielsen… - Biotechnology …, 2024 - Elsevier
Metabolic burden is defined by the influence of genetic manipulation and environmental
perturbations on the distribution of cellular resources. The rewiring of microbial metabolism …

Development of a whole-cell biosensor for detection of pyocyanin based on a transcriptional regulation factor

SJ Yue, P Huang, W Wang, HB Hu… - Sensors and Actuators B …, 2024 - Elsevier
The infection caused by multidrug-resistant bacteria Pseudomonas aeruginosa is a huge
challenge in biomedical treatment, and early identification of pathogen P. aeruginosa has …