Follicular helper T cells in the immunopathogenesis of SARS-CoV-2 infection
D Cui, Y Tang, Q Jiang, D Jiang, Y Zhang, Y Lv… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is a serious infectious disease that has led to a …
syndrome coronavirus 2 (SARS-CoV-2), is a serious infectious disease that has led to a …
T‐cell subsets in allergy and tolerance induction
I Suhrkamp, A Scheffold, G Heine - European Journal of …, 2023 - Wiley Online Library
Antigen‐specific T lymphocytes are the central regulators of tolerance versus immune
pathology against otherwise innocuous antigens and key targets of antigen‐specific immune …
pathology against otherwise innocuous antigens and key targets of antigen‐specific immune …
Peanut oral immunotherapy differentially suppresses clonally distinct subsets of T helper cells
B Monian, AA Tu, B Ruiter, DM Morgan… - The Journal of …, 2022 - Am Soc Clin Investig
Food allergy affects an estimated 8% of children in the United States. Oral immunotherapy
(OIT) is a recently approved treatment, with outcomes ranging from sustained tolerance to …
(OIT) is a recently approved treatment, with outcomes ranging from sustained tolerance to …
An update on recent developments and highlights in food allergy
While both the incidence and general awareness of food allergies is increasing, the variety
and clinical availability of therapeutics remain limited. Therefore, investigations into the …
and clinical availability of therapeutics remain limited. Therefore, investigations into the …
Immunotherapy-induced neutralizing antibodies disrupt allergen binding and sustain allergen tolerance in peanut allergy
In IgE-mediated food allergies, exposure to the allergen activates systemic allergic
responses. Oral immunotherapy (OIT) treats food allergies through incremental increases in …
responses. Oral immunotherapy (OIT) treats food allergies through incremental increases in …
Advances and potential of omics studies for understanding the development of food allergy
The prevalence of food allergy continues to rise globally, carrying with it substantial safety,
economic, and emotional burdens. Although preventative strategies do exist, the …
economic, and emotional burdens. Although preventative strategies do exist, the …
[HTML][HTML] Multi-omics profiling approach in food allergy
A Devonshire, Y Gautam, E Johansson… - World Allergy …, 2023 - Elsevier
The prevalence of food allergy (FA) among children is increasing, affecting nearly 8% of
children, and FA is the most common cause of anaphylaxis and anaphylaxis-related …
children, and FA is the most common cause of anaphylaxis and anaphylaxis-related …
T follicular helper cells in IgE-mediated pathologies
Highlights•IgE production in allergies is primarily driven by the T follicular helper (Tfh) cells,
rather than by Th2 cells.•Recent studies highlight the heterogeneity in Tfh cell populations …
rather than by Th2 cells.•Recent studies highlight the heterogeneity in Tfh cell populations …
Oral tolerance and oral immunotherapy for food allergy: Evidence for common mechanisms?
W Kazmi, MC Berin - Cellular Immunology, 2023 - Elsevier
Food allergies affect up to 10% of the US population, can be life-threatening, and have a
significant negative impact on quality of life. Delayed dietary introduction of foods in …
significant negative impact on quality of life. Delayed dietary introduction of foods in …
Biomarkers and mechanisms of tolerance induction in food allergic patients drive new therapeutic approaches
CH Baloh, MF Huffaker, T Laidlaw - Frontiers in Immunology, 2022 - frontiersin.org
Immunotherapy for food-allergic patients has been effective in inducing desensitization in
some populations, but long-term tolerance has remained an elusive target. A challenge …
some populations, but long-term tolerance has remained an elusive target. A challenge …