Coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is a serious infectious disease that has led to a …

Antigen‐specific T lymphocytes are the central regulators of tolerance versus immune
pathology against otherwise innocuous antigens and key targets of antigen‐specific immune …

Food allergy affects an estimated 8% of children in the United States. Oral immunotherapy
(OIT) is a recently approved treatment, with outcomes ranging from sustained tolerance to …

While both the incidence and general awareness of food allergies is increasing, the variety
and clinical availability of therapeutics remain limited. Therefore, investigations into the …

In IgE-mediated food allergies, exposure to the allergen activates systemic allergic
responses. Oral immunotherapy (OIT) treats food allergies through incremental increases in …

The prevalence of food allergy continues to rise globally, carrying with it substantial safety,
economic, and emotional burdens. Although preventative strategies do exist, the …

The prevalence of food allergy (FA) among children is increasing, affecting nearly 8% of
children, and FA is the most common cause of anaphylaxis and anaphylaxis-related …

Highlights•IgE production in allergies is primarily driven by the T follicular helper (Tfh) cells,
rather than by Th2 cells.•Recent studies highlight the heterogeneity in Tfh cell populations …

Food allergies affect up to 10% of the US population, can be life-threatening, and have a
significant negative impact on quality of life. Delayed dietary introduction of foods in …

Immunotherapy for food-allergic patients has been effective in inducing desensitization in
some populations, but long-term tolerance has remained an elusive target. A challenge …