Thiazole ring—A biologically active scaffold

A Petrou, M Fesatidou, A Geronikaki - Molecules, 2021 - mdpi.com
Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical
applications. Its derivatives have a wide range of biological activities such as antioxidant …

Development and therapeutic potential of 2-aminothiazole derivatives in anticancer drug discovery

SR Alizadeh, SM Hashemi - Medicinal Chemistry Research, 2021 - Springer
Currently, the development of anticancer drug resistance is significantly restricted the clinical
efficacy of the most commonly prescribed anticancer drug. Malignant disease is widely …

A retrospect on antimicrobial potential of thiazole scaffold

I Mishra, R Mishra, S Mujwar… - Journal of …, 2020 - Wiley Online Library
Due to its appreciable diversity in biological actions, thiazole and its substituted
components, a significant class of heterocyclic compounds has developed as an influential …

Anticancer potential of thiazole derivatives: a retrospective review

S Jain, S Pattnaik, K Pathak, S Kumar… - Mini reviews in …, 2018 - ingentaconnect.com
This review brings forth the potential of thiazole derivatives for their anticancer activities. The
emphasis is placed on the structural diversity of thiazole derivatives, responsible for their …

[PDF][PDF] Antibacterial activity of thiazole and its derivatives

P Mohanty, S Behera, R Behura… - … Res. Appl. Chem, 2021 - biointerfaceresearch.com
Thiazoles are one of the most intensively scrutinized classes of 5-membered aromatic
heterocycles. Many natural and synthesized thiazole and its derivatives showed significant …

Review on synthetic chemistry and antibacterial importance of thiazole derivatives

A Kashyap, N Adhikari, A Das, A Shakya… - Current drug …, 2018 - ingentaconnect.com
Background: Thiazole is one of the leading heterocyclic five-member ring compounds that
contain nitrogen and sulphur atom. Many natural and/or synthetic compounds contain …

Heterocycle compounds with antimicrobial activity

M Fesatidou, A Petrou, G Athina - Current pharmaceutical …, 2020 - ingentaconnect.com
Background: Bacterial infections are a growing problem worldwide causing morbidity and
mortality mainly in developing countries. Moreover, the increased number of …

2, 4-Disubstituted thiazoles as multitargated bioactive molecules

P Arora, R Narang, SK Nayak, SK Singh… - Medicinal Chemistry …, 2016 - Springer
Thiazoles are important heterocyclics exhibiting boundaryless biological activities, such as
antibacterial, antifungal, anti-inflammatory, antitumor, antitubercular, antidiabetic, antiviral …

Synthesis, in silico and biological studies of thiazolyl-2h-chromen-2-one derivatives as potent antitubercular agents

BS Jadhav, RS Yamgar, RS Kenny… - … -Aided Drug Design, 2020 - ingentaconnect.com
Background: A series of new six thiazolyl-2-amine-based Schiff base derivatives (4a-4f)
were synthesized by a sequential multistep reaction starting with Salicylaldehyde. Methods …

[HTML][HTML] Quorum sensing inhibitors: curbing pathogenic infections through inhibition of bacterial communication

S Singh, S Bhatia - Iranian journal of pharmaceutical research …, 2021 - ncbi.nlm.nih.gov
Currently, most of the developed and developing countries are facing the problem of
infectious diseases. The genius way of an exaggerated application of antibiotics led the …