This review focuses on the multiple and reciprocal relationships that exist between oxidative
stress, hyperglycemia and diabetes and related metabolic disorders. Human metabolism …

Numerous pharmaceutical drugs have been repurposed for use as treatments for COVID-19
disease. These drugs have not consistently demonstrated high efficacy in preventing or …

The pathogeneses of the 2 major forms of diabetes, type 1 and type 2, differ with respect to
their major molecular insults (loss of immune tolerance and onset of tissue insulin …

Arachidonic acid (AA) is a polyunsaturated 20-carbon fatty acid present in phospholipids in
the plasma membrane. The three primary pathways by which AA is metabolized are …

Platelet ACKR3/CXCR7 surface expression is enhanced and influences prognosis in
coronary artery disease (CAD) patients, who exhibit a distinct atherothrombotic platelet …

The polyamines—putrescine, spermidine, and spermine—are polycationic, low molecular
weight amines with cellular functions primarily related to mRNA translation and cell …

In this investigation, a potentially novel signaling pathway in gentamicin-induced acute
kidney injury—worsened by overexpression of proximal tubular enzyme, myo-inositol …

Liver cancer is a malignancy developed from underlying liver disease that encompasses
liver injury and metabolic disorders. The progression from these underlying liver disease to …

Recently, an increase in the incidence of inflammatory bowel disease (IBD) has been
observed, especially among children and adolescents. Currently, few studies focus on the …

Psoriatic arthritis (PsA) is a chronic, systemic, immune-mediated inflammatory disease
causing cutaneous and musculoskeletal inflammation that affects 25% of patients with …