METHODS This guideline is based on the previous colon cancer parameter published in
2017. 10 Compared with 2017, this guideline has 11 new, 10 updated, and 2 excluded …

The lungs are the second most common site of metastasis for colorectal cancer (CRC) after
the liver. Rectal cancer is associated with a higher incidence of lung metastases compared …

Pulmonary metastases are a sign of advanced malignancy and an omen of poor prognosis.
Once primary tumors metastasize, they become notoriously difficult to treat and …

Colorectal cancer (CRC) is one of the leading causes of cancer death worldwide, and
metastasis is the major cause of CRC-related mortality. Transforming growth factor-beta …

Purpose: We have reported loss of SMAD4 promotes expression of CCL15 from colorectal
cancer to recruit CCR1+ myeloid cells through the CCL15-CCR1 axis, which contributes to …

Colorectal cancer (CRC) is one of the most common causes of death from cancer. Lung
seeding occurs in approximately 10% of patients surgically treated for primary CRC with …

The incidence of pancreatic adenocarcinoma (PDAC) has steadily increased over the past
several decades. The majority of PDAC patients will present with distant metastases, limiting …

Objective: The aim of this study was to evaluate the benefit of anatomical resection (AR) in
lung metastasectomy (LM) of colorectal cancer (CRC) harboring KRAS mutations Summary …

Background: Pancreatic cancer is a highly aggressive malignancy and will become the
second leading cause of cancer-related death in the USA and also in Germany by 2030 …

Pulmonary metastasectomy (PM) is routinely performed in colorectal cancer (CRC) patients
with oligometastatic spreading to the lungs. Patients with an aggressive tumor phenotype …