PI3K/AKT/mTOR (phosphoinositide 3-kinase/protein kinase B/mammalian target of
rapamycin) signaling pathway is an important signal transduction pathway mediated by …

Off-label Use of Recombinant Activated Factor VII for Cardiac Surgical Bleeding |
Anesthesiology | American Society of Anesthesiologists Skip to Main Content Advertisement …

Rare inherited coagulation disorders due to the deficiency or dysfunction of coagulation
factors have until recently received less clinical attention than hemophilias and von …

As perioperative bleeding continues to be a major source of morbidity and mortality in
cardiac surgery, the search continues for an ideal hemostatic agent for use in this patient …

Background Rare inherited coagulation disorders due to the deficiency or dysfunction of
coagulation factors have until recently received less clinical attention than the hemophilias …

Introduction: Patients with bleeding disorders are best served by multidisciplinary teams.
Pharmacists can play a critical role in the optimal management of patients with bleeding …

Background Safety concerns exist with the off-label use of recombinant factor VIIa (rFVIIa,
Novoseven RT®) for refractory bleeding in cardiac surgery, including increased risk of …

Background: Severe bleeding is a leading cause of death among acute leukemia patients.
For those patients with non-acute promyelocytic leukemia, Platelet Transfusion …