MicroRNAs as the critical regulators of forkhead box protein family in pancreatic, thyroid, and liver cancers
The metabolism of human body is mainly regulated by the pancreas, liver, and thyroid using
the hormones or exocrine secretions that affect the metabolic processes from food digestion …
the hormones or exocrine secretions that affect the metabolic processes from food digestion …
Members of FOX family could be drug targets of cancers
J Wang, W Li, Y Zhao, DE Kang, W Fu, X Zheng… - Pharmacology & …, 2018 - Elsevier
FOX families play important roles in biological processes, including metabolism,
development, differentiation, proliferation, apoptosis, migration, invasion and longevity. Here …
development, differentiation, proliferation, apoptosis, migration, invasion and longevity. Here …
Identification of a 6-gene signature predicting prognosis for colorectal cancer
S Zuo, G Dai, X Ren - Cancer cell international, 2019 - Springer
Background An accurate and robust gene signature is of the utmost importance in assisting
oncologists to make a more accurate evaluation in clinical practice. In our study, we …
oncologists to make a more accurate evaluation in clinical practice. In our study, we …
MicroRNA-92a-1–5p increases CDX2 by targeting FOXD1 in bile acids-induced gastric intestinal metaplasia
T Li, H Guo, H Li, Y Jiang, K Zhuang, C Lei, J Wu… - Gut, 2019 - gut.bmj.com
Background and aims Gastric intestinal metaplasia (IM) is common in the gastric epithelium
of patients with chronic atrophic gastritis. CDX2 activation in IM is driven by reflux of bile …
of patients with chronic atrophic gastritis. CDX2 activation in IM is driven by reflux of bile …
[HTML][HTML] Down-regulation of miR-30a-5p is associated with poor prognosis and promotes chemoresistance of gemcitabine in pancreatic ductal adenocarcinoma
L Zhou, S Jia, G Ding, M Zhang, W Yu, Z Wu… - Journal of …, 2019 - ncbi.nlm.nih.gov
Abstract MicroRNA-30a-5p (miR-30a-5p) plays an important role in many biological and
pathological processes, and therefore has been studied extensively. However, its …
pathological processes, and therefore has been studied extensively. However, its …
The multisystemic functions of FOXD1 in development and disease
P Quintero-Ronderos, P Laissue - Journal of Molecular Medicine, 2018 - Springer
Transcription factors (TFs) participate in a wide range of cellular processes due to their
inherent function as essential regulatory proteins. Their dysfunction has been linked to …
inherent function as essential regulatory proteins. Their dysfunction has been linked to …
[HTML][HTML] FOXD1 is targeted by miR-30a-5p and miR-200a-5p and suppresses the proliferation of human ovarian carcinoma cells by promoting p21 expression in a p53 …
Y Wang, C Qiu, N Lu, Z Liu, C Jin… - International …, 2018 - spandidos-publications.com
High-grade serous ovarian carcinoma (HGSOC) accounts for the highest number of deaths
among patients with epithelial ovarian cancer. However, the molecular mechanisms …
among patients with epithelial ovarian cancer. However, the molecular mechanisms …
[HTML][HTML] FOXD1 promotes cell growth and metastasis by activation of vimentin in NSCLC
D Li, S Fan, F Yu, X Zhu, Y Song, M Ye… - Cellular physiology and …, 2019 - karger.com
Background/Aims: Forkhead box D1 (FOXD1) has a well-established role in early embryonic
development and organogenesis and functions as an oncogene in several cancers …
development and organogenesis and functions as an oncogene in several cancers …
LncRNA FOXD1‐AS1 acts as a potential oncogenic biomarker in glioma
YF Gao, JY Liu, XY Mao, ZW He, T Zhu… - CNS Neuroscience …, 2020 - Wiley Online Library
Aims Altered activities of long noncoding RNAs (lncRNAs) have been associated with
cancer development, and lncRNA FOXD1‐AS1 (FOXD1‐AS1) is the antisense transcript of …
cancer development, and lncRNA FOXD1‐AS1 (FOXD1‐AS1) is the antisense transcript of …
FOXD1 and Gal-3 form a positive regulatory loop to regulate lung cancer aggressiveness
Dysregulation of forkhead box D1 (FOXD1) is known to promote tumor progression;
however, its molecular mechanism of action is unclear. Based on microarray analysis, we …
however, its molecular mechanism of action is unclear. Based on microarray analysis, we …