Vimentin as a multifaceted player and potential therapeutic target in viral infections

I Ramos, K Stamatakis, CL Oeste… - International journal of …, 2020 - mdpi.com
Vimentin is an intermediate filament protein that plays key roles in integration of cytoskeletal
functions, and therefore in basic cellular processes such as cell division and migration …

Mechanical and non‐mechanical functions of filamentous and non‐filamentous vimentin

AE Patteson, A Vahabikashi, RD Goldman… - …, 2020 - Wiley Online Library
Intermediate filaments (IFs) formed by vimentin are less understood than their cytoskeletal
partners, microtubules and F‐actin, but the unique physical properties of IFs, especially their …

Salmonella effector SopB reorganizes cytoskeletal vimentin to maintain replication vacuoles for efficient infection

S Zhao, Q Xu, Y Cui, S Yao, S Jin, Q Zhang… - Nature …, 2023 - nature.com
A variety of intracellular bacteria modulate the host cytoskeleton to establish subcellular
niches for replication. However, the role of intermediate filaments, which are crucial for …

Invasion of the Brain by Listeria monocytogenes Is Mediated by InlF and Host Cell Vimentin

P Ghosh, EM Halvorsen, DA Ammendolia… - MBio, 2018 - Am Soc Microbiol
Listeria monocytogenes is a facultative intracellular bacterial pathogen that is frequently
associated with food-borne infection. Of particular concern is the ability of L. monocytogenes …

Cell surface detection of vimentin, ACE2 and SARS-CoV-2 Spike proteins reveals selective colocalization at primary cilia

V Lalioti, S González-Sanz, I Lois-Bermejo… - Scientific reports, 2022 - nature.com
Abstract The SARS-CoV-2 Spike protein mediates docking of the virus onto cells prior to
viral invasion. Several cellular receptors facilitate SARS-CoV-2 Spike docking at the cell …

The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the …

L Deng, BL Spencer, JA Holmes, R Mu, S Rego… - PLoS …, 2019 - journals.plos.org
Streptococcus agalactiae (Group B Streptococcus, GBS) normally colonizes healthy adults
but can cause invasive disease, such as meningitis, in the newborn. To gain access to the …

In wound repair vimentin mediates the transition of mesenchymal leader cells to a myofibroblast phenotype

JL Walker, BM Bleaken, AR Romisher… - Molecular biology of …, 2018 - Am Soc Cell Biol
Following injury, mesenchymal repair cells are activated to function as leader cells that
modulate wound healing. These cells have the potential to differentiate to myofibroblasts …

Site-specific glycosylation regulates the form and function of the intermediate filament cytoskeleton

HJ Tarbet, L Dolat, TJ Smith, BM Condon, ET O'Brien III… - elife, 2018 - elifesciences.org
Intermediate filaments (IF) are a major component of the metazoan cytoskeleton and are
essential for normal cell morphology, motility, and signal transduction. Dysregulation of IFs …

[HTML][HTML] Type III intermediate filaments as targets and effectors of electrophiles and oxidants

Á Viedma-Poyatos, MA Pajares, D Pérez-Sala - Redox biology, 2020 - Elsevier
Intermediate filaments (IFs) play key roles in cell mechanics, signaling and homeostasis.
Their assembly and dynamics are finely regulated by posttranslational modifications. The …

Vimentin modulates infectious internalization of human papillomavirus 16 pseudovirions

G Schäfer, LM Graham, DM Lang… - Journal of …, 2017 - Am Soc Microbiol
Human papillomavirus (HPV) infection is the most common viral infection of the reproductive
tract, with virtually all cases of cervical cancer being attributable to infection by oncogenic …