Vimentin as a multifaceted player and potential therapeutic target in viral infections
Vimentin is an intermediate filament protein that plays key roles in integration of cytoskeletal
functions, and therefore in basic cellular processes such as cell division and migration …
functions, and therefore in basic cellular processes such as cell division and migration …
Mechanical and non‐mechanical functions of filamentous and non‐filamentous vimentin
Intermediate filaments (IFs) formed by vimentin are less understood than their cytoskeletal
partners, microtubules and F‐actin, but the unique physical properties of IFs, especially their …
partners, microtubules and F‐actin, but the unique physical properties of IFs, especially their …
Salmonella effector SopB reorganizes cytoskeletal vimentin to maintain replication vacuoles for efficient infection
S Zhao, Q Xu, Y Cui, S Yao, S Jin, Q Zhang… - Nature …, 2023 - nature.com
A variety of intracellular bacteria modulate the host cytoskeleton to establish subcellular
niches for replication. However, the role of intermediate filaments, which are crucial for …
niches for replication. However, the role of intermediate filaments, which are crucial for …
Invasion of the Brain by Listeria monocytogenes Is Mediated by InlF and Host Cell Vimentin
P Ghosh, EM Halvorsen, DA Ammendolia… - MBio, 2018 - Am Soc Microbiol
Listeria monocytogenes is a facultative intracellular bacterial pathogen that is frequently
associated with food-borne infection. Of particular concern is the ability of L. monocytogenes …
associated with food-borne infection. Of particular concern is the ability of L. monocytogenes …
Cell surface detection of vimentin, ACE2 and SARS-CoV-2 Spike proteins reveals selective colocalization at primary cilia
V Lalioti, S González-Sanz, I Lois-Bermejo… - Scientific reports, 2022 - nature.com
Abstract The SARS-CoV-2 Spike protein mediates docking of the virus onto cells prior to
viral invasion. Several cellular receptors facilitate SARS-CoV-2 Spike docking at the cell …
viral invasion. Several cellular receptors facilitate SARS-CoV-2 Spike docking at the cell …
The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the …
L Deng, BL Spencer, JA Holmes, R Mu, S Rego… - PLoS …, 2019 - journals.plos.org
Streptococcus agalactiae (Group B Streptococcus, GBS) normally colonizes healthy adults
but can cause invasive disease, such as meningitis, in the newborn. To gain access to the …
but can cause invasive disease, such as meningitis, in the newborn. To gain access to the …
In wound repair vimentin mediates the transition of mesenchymal leader cells to a myofibroblast phenotype
JL Walker, BM Bleaken, AR Romisher… - Molecular biology of …, 2018 - Am Soc Cell Biol
Following injury, mesenchymal repair cells are activated to function as leader cells that
modulate wound healing. These cells have the potential to differentiate to myofibroblasts …
modulate wound healing. These cells have the potential to differentiate to myofibroblasts …
Site-specific glycosylation regulates the form and function of the intermediate filament cytoskeleton
Intermediate filaments (IF) are a major component of the metazoan cytoskeleton and are
essential for normal cell morphology, motility, and signal transduction. Dysregulation of IFs …
essential for normal cell morphology, motility, and signal transduction. Dysregulation of IFs …
[HTML][HTML] Type III intermediate filaments as targets and effectors of electrophiles and oxidants
Á Viedma-Poyatos, MA Pajares, D Pérez-Sala - Redox biology, 2020 - Elsevier
Intermediate filaments (IFs) play key roles in cell mechanics, signaling and homeostasis.
Their assembly and dynamics are finely regulated by posttranslational modifications. The …
Their assembly and dynamics are finely regulated by posttranslational modifications. The …
Vimentin modulates infectious internalization of human papillomavirus 16 pseudovirions
Human papillomavirus (HPV) infection is the most common viral infection of the reproductive
tract, with virtually all cases of cervical cancer being attributable to infection by oncogenic …
tract, with virtually all cases of cervical cancer being attributable to infection by oncogenic …