Mammography/tomosynthesis systems and methods automatically deriving breast characteristics from breast X-ray images and automatically adjusting image …
AP Smith, B Chen, Z Jing - US Patent 8,170,320, 2012 - Google Patents
BACKGROUND The breast images obtained directly from digital X-ray receptors typically
are not suitable for screening or diagnosis and need to be computer-processed by …
are not suitable for screening or diagnosis and need to be computer-processed by …
Anti-human DLL4 antibodies and compositions
A Gurney, F Axelrod, T Hoey, S Satyal - US Patent 7,750,124, 2010 - Google Patents
Related US Application Data GB 2449354 A 11, 2008 (60) Provisional application No.
60/942.542, filed on Jun. WO WO92, 19734 11, 1992 7, 2007, provisional application No …
60/942.542, filed on Jun. WO WO92, 19734 11, 1992 7, 2007, provisional application No …
Antibodies to notch receptors
AL Gurney, TC Hoey, ETH van der Horst… - US Patent …, 2012 - Google Patents
2009-12-15 Assigned to ONCOMED PHARMACEUTICALS, INC. reassignment ONCOMED
PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
Hedgehog signaling pathway antagonist cancer treatment
The present invention provides methods and compositions for treating tumorigenic cells (eg,
mammary progenitor cancer cells), with hedgehog signaling pathway antagonists (eg …
mammary progenitor cancer cells), with hedgehog signaling pathway antagonists (eg …
Antibodies to notch receptors
JA Lewicki, A Gurney, T Hoey, WC Yen… - US Patent …, 2011 - Google Patents
The present invention relates to compositions and methods for characterizing, diagnosing,
and treating cancer. In par ticular the invention provides the means and methods for the …
and treating cancer. In par ticular the invention provides the means and methods for the …
VEGF/DLL4 binding agents and uses thereof
The present invention relates to VEGF-binding agents, DLL4-binding agents, VEGF/DLL4
bispecific binding agents, and methods of using the agents for treating diseases such as …
bispecific binding agents, and methods of using the agents for treating diseases such as …
Methods of treatment by administering antibodies to notch receptors
AL Gurney, TC Hoey, ETH van der Horst… - US Patent …, 2013 - Google Patents
2012-08-02 Assigned to ONCOMED PHARMACEUTICALS, INC. reassignment ONCOMED
PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
Compositions and methods for diagnosing and treating cancer
AL Gurney, FT Axelrod, TC Hoey, SH Satyal - US Patent 9,228,020, 2016 - Google Patents
Anisolated antibody that specifically binds to an extracellular domain of human DLL4 and
affects growth of a tumor com prising cancer stem cells is described. Also described is a …
affects growth of a tumor com prising cancer stem cells is described. Also described is a …
Modified immunoglobulin molecules that specifically bind human VEGF and DLL4
The present invention relates to VEGF-binding agents, DLL4-binding agents, VEGF/DLL4
bispecific binding agents, and methods of using the agents for treating diseases such as …
bispecific binding agents, and methods of using the agents for treating diseases such as …
Methods of Treatment with DLL4 Antagonists and an Anti-hypertensive Agent
RJ Stagg, SE Benner - US Patent 8,883,145, 2014 - Google Patents
Methods for treating cancer comprising administering a DLL4 antagonist and one or more
anti-hypertensive agents are described. Also described are pharmaceutical composi tions …
anti-hypertensive agents are described. Also described are pharmaceutical composi tions …