BDNF as a promising therapeutic agent in Parkinson's disease

E Palasz, A Wysocka, A Gasiorowska… - International journal of …, 2020 - mdpi.com
Brain-derived neurotrophic factor (BDNF) promotes neuroprotection and neuroregeneration.
In animal models of Parkinson's disease (PD), BDNF enhances the survival of dopaminergic …

Virtual reality in research and rehabilitation of gait and balance in Parkinson disease

CG Canning, NE Allen, E Nackaerts, SS Paul… - Nature Reviews …, 2020 - nature.com
Virtual reality (VR) technology has emerged as a promising tool for studying and
rehabilitating gait and balance impairments in people with Parkinson disease (PD) as it …

Physical therapist management of Parkinson disease: a clinical practice guideline from the American Physical Therapy Association

JA Osborne, R Botkin, C Colon-Semenza… - Physical …, 2022 - academic.oup.com
A clinical practice guideline on Parkinson disease was developed by an American Physical
Therapy Association volunteer guideline development group that consisted of physical …

Physical exercise improves quality of life, depressive symptoms, and cognition across chronic brain disorders: a transdiagnostic systematic review and meta-analysis …

M Dauwan, MJH Begemann, MIE Slot, EHM Lee… - Journal of …, 2021 - Springer
We performed a meta-analysis to synthesize evidence on the efficacy and safety of physical
exercise as an add-on therapeutic intervention for quality of life (QoL), depressive symptoms …

The benefits and mechanisms of exercise training for Parkinson's disease

YS Feng, SD Yang, ZX Tan, MM Wang, Y Xing, F Dong… - Life sciences, 2020 - Elsevier
Parkinson's disease (PD) is a significantly progressive neurodegenerative disease
characterised by both motor and nonmotor disorders. The main pathological characteristics …

Nonpharmacological treatments for patients with Parkinson's disease

BR Bloem, NM de Vries, G Ebersbach - Movement Disorders, 2015 - Wiley Online Library
Since 2013, a number of studies have enhanced the literature and have guided clinicians on
viable treatment interventions outside of pharmacotherapy and surgery. Thirty‐three …

Effects of exercise on falls, balance, and gait ability in Parkinson's disease: a meta-analysis

X Shen, ISK Wong-Yu… - … and neural repair, 2016 - journals.sagepub.com
Postural instability and falls are complex and disabling features of Parkinson's disease (PD)
and respond poorly to anti-Parkinsonian medication. There is an imperative need to …

Evidence for early and regular physical therapy and exercise in Parkinson's disease

TD Ellis, C Colón-Semenza, TR DeAngelis… - Seminars in …, 2021 - thieme-connect.com
Advances in medical management of Parkinson's disease (PD) have resulted in living
longer with disability. Although disability worsens over the course of the disease, there are …

A motion capturing and energy harvesting hybridized lower‐limb system for rehabilitation and sports applications

S Gao, T He, Z Zhang, H Ao, H Jiang… - Advanced …, 2021 - Wiley Online Library
Lower‐limb motion monitoring is highly desired in various application scenarios ranging
from rehabilitation to sports training. However, there still lacks a cost‐effective, energy …

The effects of physical activity in Parkinson's disease: a review

M Lauzé, JF Daneault, C Duval - Journal of Parkinson's …, 2016 - content.iospress.com
Background: Physical activity (PA) is increasingly advocated as an adjunct intervention for
individuals with Parkinson's disease (PD). However, the specific benefits of PA on the wide …