Opportunities and challenges of using metagenomic data to bring uncultured microbes into cultivation

S Liu, CD Moon, N Zheng, S Huws, S Zhao, J Wang - Microbiome, 2022 - Springer
Although there is now an extensive understanding of the diversity of microbial life on earth
through culture-independent metagenomic DNA sequence analyses, the isolation and …

Alternaria Toxins: Potential Virulence Factors and Genes Related to Pathogenesis

M Meena, SK Gupta, P Swapnil, A Zehra… - Frontiers in …, 2017 - frontiersin.org
Alternaria is an important fungus to study due to their different life style from saprophytes to
endophytes and a very successful fungal pathogen that causes diseases to a number of …

dbCAN3: automated carbohydrate-active enzyme and substrate annotation

J Zheng, Q Ge, Y Yan, X Zhang, L Huang… - Nucleic Acids …, 2023 - academic.oup.com
Carbohydrate active enzymes (CAZymes) are made by various organisms for complex
carbohydrate metabolism. Genome mining of CAZymes has become a routine data analysis …

[HTML][HTML] Gut-microbiota-targeted diets modulate human immune status

HC Wastyk, GK Fragiadakis, D Perelman, D Dahan… - Cell, 2021 - cell.com
Diet modulates the gut microbiome, which in turn can impact the immune system. Here, we
determined how two microbiota-targeted dietary interventions, plant-based fiber and …

Differential peripheral immune signatures elicited by vegan versus ketogenic diets in humans

VM Link, P Subramanian, F Cheung, KL Han, A Stacy… - Nature medicine, 2024 - nature.com
Nutrition has broad impacts on all physiological processes. However, how nutrition affects
human immunity remains largely unknown. Here we explored the impact of a dietary …

Updating species diversity of Colletotrichum, with a phylogenomic overview

F Liu, ZY Ma, LW Hou, YZ Diao, WP Wu… - Studies in …, 2022 - ingentaconnect.com
The genus Colletotrichum includes important plant pathogens, endophytes, saprobes and
human pathogens. Even though the polyphasic approach has facilitatedColletotrichum …

Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease

KL Bowerman, SF Rehman, A Vaughan… - Nature …, 2020 - nature.com
Chronic obstructive pulmonary disease (COPD) is the third commonest cause of death
globally, and manifests as a progressive inflammatory lung disease with no curative …

[HTML][HTML] Elevated rates of horizontal gene transfer in the industrialized human microbiome

M Groussin, M Poyet, A Sistiaga, SM Kearney, K Moniz… - Cell, 2021 - cell.com
Industrialization has impacted the human gut ecosystem, resulting in altered microbiome
composition and diversity. Whether bacterial genomes may also adapt to the …

Isolation of an archaeon at the prokaryote–eukaryote interface

H Imachi, MK Nobu, N Nakahara, Y Morono… - Nature, 2020 - nature.com
The origin of eukaryotes remains unclear,,–. Current data suggest that eukaryotes may have
emerged from an archaeal lineage known as 'Asgard'archaea,. Despite the eukaryote-like …

Disease-induced changes in plant microbiome assembly and functional adaptation

M Gao, C Xiong, C Gao, CKM Tsui, MM Wang, X Zhou… - Microbiome, 2021 - Springer
Background The plant microbiome is an integral part of the host and increasingly recognized
as playing fundamental roles in plant growth and health. Increasing evidence indicates that …