Incorporating pathway information into feature selection towards better performed gene signatures

S Tian, C Wang, B Wang - BioMed research international, 2019 - Wiley Online Library
To analyze gene expression data with sophisticated grouping structures and to extract
hidden patterns from such data, feature selection is of critical importance. It is well known …

Multi-omics facilitated variable selection in Cox-regression model for cancer prognosis prediction

C Liu, X Wang, GZ Genchev, H Lu - Methods, 2017 - Elsevier
Motivation New developments in high-throughput genomic technologies have enabled the
measurement of diverse types of omics biomarkers in a cost-efficient and clinically-feasible …

MicroRNA databases and tools

TS de Amorim, DLF Pedro, AR Paschoal - miRNomics: MicroRNA Biology …, 2022 - Springer
In this era of big data, sets of methodologies and strategies are designed to extract
knowledge from huge volumes of data. However, the cost of where and how to get this …

High-dimensional omics data analysis using a variable screening protocol with prior knowledge integration (SKI)

C Liu, J Jiang, J Gu, Z Yu, T Wang, H Lu - BMC systems biology, 2016 - Springer
Background High-throughput technology could generate thousands to millions biomarker
measurements in one experiment. However, results from high throughput analysis are often …

Ultra-high dimensional variable selection with application to normative aging study: DNA methylation and metabolic syndrome

G Yoon, Y Zheng, Z Zhang, H Zhang, T Gao, B Joyce… - BMC …, 2017 - Springer
Background Metabolic syndrome has become a major public health challenge worldwide.
The association between metabolic syndrome and DNA methylation is of great research …

Feature selection for longitudinal data by using sign averages to summarize gene expression values over time

S Tian, C Wang - BioMed Research International, 2019 - Wiley Online Library
With the rapid evolution of high‐throughput technologies, time series/longitudinal high‐
throughput experiments have become possible and affordable. However, the development …

GEE‐TGDR: A Longitudinal Feature Selection Algorithm and Its Application to lncRNA Expression Profiles for Psoriasis Patients Treated with Immune Therapies

S Tian, C Wang… - BioMed Research …, 2021 - Wiley Online Library
With the fast evolution of high‐throughput technology, longitudinal gene expression
experiments have become affordable and increasingly common in biomedical fields …

[PDF][PDF] Topics of Variable Selection in Biomedical Data Mining

G Yoon - 2017 - scholar.archive.org
Background “Among plausible explanations for a phenomenon, the simplest is the best.”–
Principle of Occam's razor Variable selection problem has been extensively studied in …