A simple HPLC method for the quantitative determination of silybin in rat plasma: Application to a comparative pharmacokinetic study on commercial silymarin …
Silybin (SBN) is a major active constituent of silymarin, a mixture of flavonoids found in fruits
and seeds of milk thistle. The aim of this study was to describe a simple bioanalytical method …
and seeds of milk thistle. The aim of this study was to describe a simple bioanalytical method …
Differential regulation of intestinal and hepatic CYP3A by 1α,25‐dihydroxyvitamin D3: Effects on in vivo oral absorption and disposition of buspirone in rats
Abstract 1α, 25‐Dihydroxyvitamin D3 (also called 1, 25 (OH) 2D3 or calcitriol) is the
biologically active form of vitamin D, which functions as a ligand to the vitamin D receptor …
biologically active form of vitamin D, which functions as a ligand to the vitamin D receptor …
Novel reverse electrodialysis-driven iontophoretic system for topical and transdermal delivery of poorly permeable therapeutic agents
KT Kim, J Lee, MH Kim, JH Park, JY Lee, JH Song… - Drug Delivery, 2017 - Taylor & Francis
Topical and transdermal drug delivery has great potential in non-invasive and non-oral
administration of poorly bioavailable therapeutic agents. However, due to the barrier …
administration of poorly bioavailable therapeutic agents. However, due to the barrier …
Modulation of rat hepatic CYP1A and 2C activity by honokiol and magnolol: Differential effects on phenacetin and diclofenac pharmacokinetics in vivo
SB Kim, KS Kim, HM Ryu, SH Hong, BK Kim, DD Kim… - Molecules, 2018 - mdpi.com
Honokiol (2-(4-hydroxy-3-prop-2-enyl-phenyl)-4-prop-2-enyl-phenol) and magnolol (4-Allyl-
2-(5-allyl-2-hydroxy-phenyl) phenol) are the major active polyphenol constituents of …
2-(5-allyl-2-hydroxy-phenyl) phenol) are the major active polyphenol constituents of …
Simultaneous Determination of Schisandrin and Promethazine with Its Metabolite in Rat Plasma by HPLC‐MS/MS and Its Application to a Pharmacokinetic Study
S Gao, X Zhou, L Lang, H Liu, J Li, H Li… - … Journal of Analytical …, 2019 - Wiley Online Library
This study aimed to develop a selective, simple, and sensitive HPLC‐MS/MS method for the
simultaneous determination of schisandrin and promethazine (PMZ) with its metabolite in rat …
simultaneous determination of schisandrin and promethazine (PMZ) with its metabolite in rat …