Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …

Tissue repair and regeneration after damage is not completely understood, and current
therapies to support this process are limited. The wound healing process is associated with …

As the most dominant cell type in the skin, keratinocytes play critical roles in wound repair
not only as structural cells but also exerting important immune functions. This review focuses …

Although stem cell-based therapy has demonstrated considerable potential to manage
certain diseases more successfully than conventional surgery, it nevertheless comes with …

Wound healing is a dynamic and highly sequential process involving a series of overlapping
spatial and temporal phases, including hemostasis, inflammation, proliferation, and tissue …

Accumulating reports indicate that adipose-derived stem cell (ADSC)-originating exosomes
(ADSC-Exos) provide a potential strategy for diabetic wound repair. However, the …

Background Hypertrophic scar (HS) is a fibro-proliferative disorder of dermis after burn or
trauma and usually leads to esthetic disfiguration and functionary impairment for patients …

Extracellular vesicles (EVs) derived from mesenchymal stem cells isolated from both bone
marrow (BMSCs) and adipose tissue (ADSCs) show potential therapeutic effects. These …

The therapeutic benefits of mesenchymal stromal cell (MSC) transplantation are attributed to
their secreted factors, including extracellular vesicles (EVs) and soluble factors. The …

The cells secrete extracellular vesicles (EV) that may have an endosomal origin, or from
evaginations of the plasma membrane. The former are usually called exosomes, with sizes …