Spatial normalization and quantification approaches of PET imaging for neurological disorders

T Zhang, S Wu, X Zhang, Y Dai, A Wang… - European Journal of …, 2022 - Springer
Quantification approaches of positron emission tomography (PET) imaging provide user-
independent evaluation of pathophysiological processes in living brains, which have been …

Clinical validity of increased cortical binding of tau ligands of the THK family and PBB3 on PET as biomarkers for Alzheimer's disease in the context of a structured 5 …

K Chiotis, A Dodich, M Boccardi, C Festari… - European journal of …, 2021 - Springer
Purpose The research community has focused on defining reliable biomarkers for the early
detection of the pathological hallmarks of Alzheimer's disease (AD). In 2017, the Geneva AD …

Gaussian discriminative component analysis for early detection of Alzheimer's disease: A supervised dimensionality reduction algorithm

C Fang, C Li, P Forouzannezhad, M Cabrerizo… - Journal of neuroscience …, 2020 - Elsevier
Background Using multiple modalities of biomarkers, several machine leaning-based
approaches have been proposed to characterize patterns of structural, functional and …

Feasibility of 18F-florzolotau quantification in patients with Alzheimer's disease based on an MRI-free tau PET template

J Lu, Z Ju, M Wang, X Sun, C Jia, L Li, W Bao… - European …, 2023 - Springer
Objectives Quantification of tau accumulation using positron emission tomography (PET) is
critical for the diagnosis of Alzheimer's disease (AD). This study aimed to evaluate the …

An efficient method for detection of Alzheimer's disease using high-dimensional PET scan images

A Borji, A Seifi, TH Hejazi - Intelligent Decision Technologies, 2023 - content.iospress.com
The significance of data analytics and machine learning has increased in managing vast
quantities of healthcare data effectively. According to recent statistics, Alzheimer's disease is …

Unified spatial normalization method of brain PET images using adaptive probabilistic brain atlas

T Zhang, B Nie, H Liu, B Shan… - European Journal of …, 2022 - Springer
Purpose A unique advantage of the brain positron emission tomography (PET) imaging is
the ability to image different biological processes with different radiotracers. However, the …

[HTML][HTML] Development and evaluation of a T1 standard brain template for Alzheimer disease

XY Guo, Y Chang, Y Kim, HY Rhee… - … Imaging in Medicine …, 2021 - ncbi.nlm.nih.gov
Background Patients with Alzheimer disease (AD) and mild cognitive impairment (MCI) have
high variability in brain tissue loss, making it difficult to use a disease-specific standard brain …

Introducing an ensemble method for the early detection of Alzheimer's disease through the analysis of PET scan images

A Borji, TH Hejazi, A Seifi - arXiv preprint arXiv:2403.15443, 2024 - arxiv.org
Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects
cognitive functions such as memory, thinking, and behavior. In this disease, there is a critical …

TauAD: MRI-free Tau Anomaly Detection in PET Imaging via Conditioned Diffusion Models

L Zhong, S Huang, J Yue, J Zhang, Z Deng… - arXiv preprint arXiv …, 2024 - arxiv.org
The emergence of tau PET imaging over the last decade has enabled Alzheimer's disease
(AD) researchers to examine tau pathology in vivo and more effectively characterize the …

Comparison of MRI-based and PET-based image pre-processing for quantification of 11C-PBB3 uptake in human brain

E Yousefzadeh-Nowshahr, G Winter, P Bohn… - … für Medizinische Physik, 2021 - Elsevier
Purpose Quantification of tau load using 11 C-PBB3-PET has the potential to improve
diagnosis of neurodegenerative diseases. Although MRI-based pre-processing is used as a …