[HTML][HTML] Glutamine: metabolism and immune function, supplementation and clinical translation
Glutamine is the most abundant and versatile amino acid in the body. In health and disease,
the rate of glutamine consumption by immune cells is similar or greater than glucose. For …
the rate of glutamine consumption by immune cells is similar or greater than glucose. For …
Inflammation and oxidative stress: the molecular connectivity between insulin resistance, obesity, and Alzheimer's disease
Type 2 diabetes (T2DM), Alzheimer's disease (AD), and insulin resistance are age‐related
conditions and increased prevalence is of public concern. Recent research has provided …
conditions and increased prevalence is of public concern. Recent research has provided …
Molecular Events Linking Oxidative Stress and Inflammation to Insulin Resistance and β‐Cell Dysfunction
The prevalence of diabetes mellitus (DM) is increasing worldwide, a consequence of the
alarming rise in obesity and metabolic syndrome (MetS). Oxidative stress and inflammation …
alarming rise in obesity and metabolic syndrome (MetS). Oxidative stress and inflammation …
[HTML][HTML] The role of oxidative stress in the development of diabetes mellitus and its complications
JM Dos Santos, S Tewari… - Journal of diabetes …, 2019 - ncbi.nlm.nih.gov
The thematic issue addresses the role of oxidative stress in the development of diabetes and
its related complications. Diabetes is a growing pandemic of the 21st century that has …
its related complications. Diabetes is a growing pandemic of the 21st century that has …
Amino acid supplementation and impact on immune function in the context of exercise
Moderate and chronic bouts of exercise may lead to positive metabolic, molecular, and
morphological adaptations, improving health. Although exercise training stimulates the …
morphological adaptations, improving health. Although exercise training stimulates the …
The chaperone balance hypothesis: The importance of the extracellular to intracellular HSP70 ratio to inflammation‐driven type 2 diabetes, the effect of exercise, and …
Recent evidence shows divergence between the concentrations of extracellular 70 kDa heat
shock protein [eHSP70] and its intracellular concentrations [iHSP70] in people with type 2 …
shock protein [eHSP70] and its intracellular concentrations [iHSP70] in people with type 2 …
Targeting the molecular & cellular pillars of human aging with exercise
Biological aging is the main driver of age‐associated chronic diseases. In 2014, the United
States National Institute of Aging (NIA) sponsored a meeting between several investigators …
States National Institute of Aging (NIA) sponsored a meeting between several investigators …
[HTML][HTML] Down syndrome is a metabolic disease: altered insulin signaling mediates peripheral and brain dysfunctions
M Dierssen, M Fructuoso… - Frontiers in …, 2020 - frontiersin.org
Down syndrome (DS) is the most frequent chromosomal abnormality that causes intellectual
disability, resulting from the presence of an extra complete or segment of chromosome 21 …
disability, resulting from the presence of an extra complete or segment of chromosome 21 …
[HTML][HTML] The abnormal level of HSP70 is related to Treg/Th17 imbalance in PCOS patients
Y Yang, J Xia, Z Yang, G Wu, J Yang - Journal of Ovarian Research, 2021 - Springer
Background Polycystic ovary syndrome (PCOS) is a disease with chronic nonspecific low-
grade inflammation. The imbalance of immune cells exists in PCOS. Several studies have …
grade inflammation. The imbalance of immune cells exists in PCOS. Several studies have …
Suppressed anti-inflammatory heat shock response in high-risk COVID-19 patients: lessons from basic research (inclusive bats), light on conceivable therapies
The major risk factors to fatal outcome in COVID-19 patients, ie, elderliness and pre-existing
metabolic and cardiovascular diseases (CVD), share in common the characteristic of being …
metabolic and cardiovascular diseases (CVD), share in common the characteristic of being …