Diabetes and associated complications in the South Asian population

A Shah, AM Kanaya - Current cardiology reports, 2014 - Springer
The rising prevalence of diabetes in South Asians has significant health and economic
implications. South Asians are predisposed to the development of diabetes due to biologic …

[HTML][HTML] Coronary heart disease in type 2 diabetes mellitus: genetic factors and their mechanisms, gene-gene, and gene-environment interactions in the asian …

KA Zarkasi, NA Abdul Murad, N Ahmad… - International Journal of …, 2022 - mdpi.com
Asians are more susceptible to type 2 diabetes mellitus (T2D) and its coronary heart disease
(CHD) complications than the Western populations, possibly due to genetic factors, higher …

[HTML][HTML] Genetic variability in antioxidative and inflammatory pathways modifies the risk for PCOS and influences metabolic profile of the syndrome

R Herman, M Jensterle, A Janež, K Goričar, V Dolžan - Metabolites, 2020 - mdpi.com
Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder of
multifactorial etiopathology likely to involve the interactions between genetics and lifestyle …

[HTML][HTML] Investigation of Calpain 10 (rs2975760) gene polymorphism in Asian Indians with gestational diabetes mellitus

IA Khan, S Movva, NA Shaik, S Chava, P Jahan… - Meta Gene, 2014 - Elsevier
Abstract Background Type 2 Diabetes Mellitus (T2DM) and Gestational Diabetes Mellitus
(GDM) are part of a heterogeneous and complex metabolic group of disorders that share …

European versus Asian differences for the associations between paraoxonase‐1 genetic polymorphisms and susceptibility to type 2 diabetes mellitus

JQ Luo, H Ren, MZ Liu, PF Fang… - Journal of cellular and …, 2018 - Wiley Online Library
Many studies have examined the associations between paraoxonase‐1 (PON1) genetic
polymorphisms (Q192R, rs662 and L55M, rs854560) and the susceptibility to type 2 …

[HTML][HTML] Positive Association between APOA5 rs662799 Polymorphism and Coronary Heart Disease: A Case-Control Study and Meta-Analysis

H Ye, A Zhou, Q Hong, L Tang, X Xu, Y Xin, D Jiang… - PLoS …, 2015 - journals.plos.org
Objective Apolipoprotein A5 (APOA5) is associated with plasma triglyceride (TG) levels, a
risk factor for coronary heart disease (CHD). This study explored the association between …

Additional Common Polymorphisms in the PON Gene Cluster Predict PON1 Activity but Not Vascular Disease

DS Kim, AA Burt, JE Ranchalis, RJ Richter… - Journal of …, 2012 - Wiley Online Library
Background. Paraoxonase 1 (PON1) enzymatic activity has been consistently predictive of
cardiovascular disease, while the genotypes at the four functional polymorphisms at PON1 …

Paraoxonase 1 gene (Q192R) polymorphism confers susceptibility to coronary artery disease in type 2 diabetes patients: Evidence from case-control studies

X Huo, Y Guo, Y Zhang, J Li, X Wen… - Drug Discoveries & …, 2019 - jstage.jst.go.jp
Numerous published studies have investigated the relationship between the paraoxonase 1
(PON1) gene Q192R (rs662) polymorphism and the risk of coronary artery disease (CAD) in …

Relationship between the paraoxonase 1 gene glutamine 192 to arginine polymorphism and gestational diabetes mellitus in Saudi women

MM Al-Hakeem, Z Abotalib, KK Alharbi, IA Khan - Clinical biochemistry, 2014 - Elsevier
Objectives Gestational diabetes mellitus (GDM) is recognized as an imbalance between
insulin resistance and insulin secretion, leading to maternal hyperglycemia. Previous …

[HTML][HTML] Genetic associations with diabetes: meta-analyses of 10 candidate polymorphisms

L Tang, L Wang, Q Liao, Q Wang, L Xu, S Bu… - PLoS …, 2013 - journals.plos.org
Aims The goal of our study is to investigate the combined contribution of 10 genetic variants
to diabetes susceptibility. Methods Bibliographic databases were searched from 1970 to …