Manipulating the destiny of wild populations using CRISPR

R Raban, JM Marshall, BA Hay… - Annual review of …, 2023 - annualreviews.org
Genetic biocontrol aims to suppress or modify populations of species to protect public
health, agriculture, and biodiversity. Advancements in genome engineering technologies …

CRISPR/Cas9-based split homing gene drive targeting doublesex for population suppression of the global fruit pest Drosophila suzukii

AK Yadav, C Butler, A Yamamoto… - Proceedings of the …, 2023 - National Acad Sciences
Genetic-based methods offer environmentally friendly species-specific approaches for
control of insect pests. One method, CRISPR homing gene drive that target genes essential …

Biotechnology-enhanced genetic controls of the global pest Drosophila suzukii

Y Yan, HMM Ahmed, EA Wimmer, MF Schetelig - Trends in Biotechnology, 2024 - cell.com
Abstract Spotted wing Drosophila (Drosophila suzukii Matsumura, or SWD), an insect pest of
soft-skinned fruits native to East Asia, has rapidly spread worldwide in the past 15 years …

Targeting sex determination to suppress mosquito populations

M Li, NP Kandul, R Sun, T Yang, ED Benetta… - Elife, 2024 - elifesciences.org
Each year, hundreds of millions of people are infected with arboviruses such as dengue,
yellow fever, chikungunya, and Zika, which are all primarily spread by the notorious …

Eliminating malaria vectors with precision-guided sterile males

RA Apte, AL Smidler, JJ Pai, ML Chow, S Chen… - Proceedings of the …, 2024 - pnas.org
Controlling the principal African malaria vector, the mosquito Anopheles gambiae, is
considered essential to curtail malaria transmission. However, existing vector control …

[HTML][HTML] Eliminating malaria vectors with precision guided sterile males

AL Smidler, RA Apte, JJ Pai, ML Chow, S Chen… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Controlling the principal African malaria vector, the mosquito Anopheles gambiae, is
considered essential to curtail malaria transmission. However existing vector control …

Doublesex is essential for masculinization but not feminization in Lygus hesperus

JJ Hull, CC Heu, RJ Gross, DM LeRoy… - Insect Biochemistry and …, 2024 - Elsevier
In most holometabolous insects, sex differentiation occurs via a hierarchical cascade of
transcription factors, with doublesex (dsx) regulating genes that control sex-specific traits …

[HTML][HTML] Targeting sex determination to suppress mosquito populations

O Akbari, M Li, N Kandul, R Sun, T Yang… - Research …, 2023 - ncbi.nlm.nih.gov
Each year, hundreds of millions of people are infected with arboviruses such as dengue,
yellow fever, chikungunya, and Zika, which are all primarily spread by the notorious …

Cost-effectiveness of Precision Guided SIT for Control of Anopheles gambiae in the Upper River Region, The Gambia

WAC Gendron, R Raban, A Mondal, HM Sánchez C… - bioRxiv, 2023 - biorxiv.org
Precision-guided sterile insect technique (pgSIT) is an extremely promising vector control
intervention that can reduce and potentially eliminate the unacceptable malaria burden …

β-tubulin functions in spermatogenesis in Lygus hesperus Knight

CC Heu, KP Le, RJ Gross, IX Schutze… - Journal of Insect …, 2024 - Elsevier
Lygus hesperus Knight is an important insect pest of crops across western North America,
with field management heavily reliant on the use of chemical insecticides. Because of the …