Artemisinin-type drugs for the treatment of hematological malignancies

RI Mancuso, MA Foglio, ST Olalla Saad - Cancer chemotherapy and …, 2021 - Springer
Qinghaosu, known as artemisinin (ARS), has been for over two millennia, one of the most
common herbs prescribed in traditional Chinese medicine (TCM). ARS was developed as …

Hydrogel-forming microarray patches with cyclodextrin drug reservoirs for long-acting delivery of poorly soluble cabotegravir sodium for HIV Pre-Exposure Prophylaxis

F Volpe-Zanutto, LK Vora, IA Tekko… - Journal of Controlled …, 2022 - Elsevier
Hydrogel-forming microarray patches (HF-MAPs) offer minimally invasive, pain-free and
prolonged drug delivery. These devices are designed to be self-administered and self …

Bioadhesives for clinical applications–a mini review

K Uma - Materials Advances, 2023 - pubs.rsc.org
Bioadhesives are highly biocompatible and biodegradable polymers, which are used to join
two surfaces where at least one of them is a living tissue. Bioadhesives are used for various …

Vitamin D and curcumin-loaded PCL nanofibrous for engineering osteogenesis and immunomodulatory scaffold

AM Al-Bishari, BA Al-Shaaobi, AA Al-Bishari… - … in Bioengineering and …, 2022 - frontiersin.org
The accelerating bone healing process is still a major challenge in clinical orthopedics,
especially in critical-sized bone defects. Recently, Nanofiber membranes are showing …

Artemether and lumefantrine dissolving microneedle patches with improved pharmacokinetic performance and antimalarial efficacy in mice infected with Plasmodium …

F Volpe-Zanutto, LT Ferreira, AD Permana… - Journal of controlled …, 2021 - Elsevier
Malaria affects more than 200 million people annually around the world, killing a child every
2 min. Artemether (ART) and lumefantrine (LUM) are the gold standard choice to treat …

Electrospun PCL-based nanofibers Arrabidaea chica Verlot–Pterodon pubescens Benth loaded: synergic effect in fibroblast formation

THC Salles, F Volpe-Zanutto… - Biomedical …, 2020 - iopscience.iop.org
The guided tissue regeneration (GTR) technique can be applied in dentistry and other
medical specializations, such as orthopedics. In modern dentistry, GTR has been used in …

Novel transdermal bioadhesive surfactant-based system for release and solubility improvement of antimalarial drugs artemether-lumefantrine

F Volpe-Zanutto, B Fonseca-Santos… - Biomedical …, 2021 - iopscience.iop.org
Artemether (ART) and lumefantrine (LUM) are the gold standard antimalarial drugs used for
the treatment of malaria in children and pregnant women. Typically, ART and LUM are …

The modulatory effect of Artemisia annua L. on toll-like receptor expression in Acanthamoeba infected mouse lungs

A Wojtkowiak-Giera, M Derda, D Kosik-Bogacka… - Experimental …, 2019 - Elsevier
The genus Acanthamoeba, which may cause different infections in humans, occurs widely in
the environment. Lung inflammation caused by these parasites induces pulmonary …

New derivatives of 3-azabicyclo [3.2. 2] nonanes and their antiprotozoal activities

M Hoffelner, M Petritsch, S Ahmad… - Monatshefte für Chemie …, 2019 - Springer
Abstract New derivatives of 3-azabicyclo [3.2. 2] nonanes were prepared and characterized
using FT-IR spectroscopy, HRMS, and NMR spectroscopy. The new compounds were …

Transdermal antimalarial drug delivery to improve poor adherence to antimalarials: A new light at the end of the tunnel

CE Agbo, UE Chima, SC Ogbobe, FO Omotayo… - American Journal of …, 2023 - ajbps.org
Malaria, a perilous disease caused by Plasmodium parasites and characterized by a
substantial mortality rate, has persistently posed as a global health challenge. Conventional …