How the PhoP/PhoQ System Controls Virulence and Mg2+ Homeostasis: Lessons in Signal Transduction, Pathogenesis, Physiology, and Evolution
SUMMARY The PhoP/PhoQ two-component system governs virulence, Mg2+ homeostasis,
and resistance to a variety of antimicrobial agents, including acidic pH and cationic …
and resistance to a variety of antimicrobial agents, including acidic pH and cationic …
Evolution of Salmonella-Host Cell Interactions through a Dynamic Bacterial Genome
Salmonella Typhimurium has a broad arsenal of genes that are tightly regulated and
coordinated to facilitate adaptation to the various host environments it colonizes. The …
coordinated to facilitate adaptation to the various host environments it colonizes. The …
Architecture of the Escherichia coli nucleoid
SC Verma, Z Qian, SL Adhya - PLoS genetics, 2019 - journals.plos.org
How genomes are organized within cells and how the 3D architecture of a genome
influences cellular functions are significant questions in biology. A bacterial genomic DNA …
influences cellular functions are significant questions in biology. A bacterial genomic DNA …
Localized modulation of DNA supercoiling, triggered by the Shigella anti-silencer VirB, is sufficient to relieve H-NS-mediated silencing
MA Picker, MMA Karney, TM Gerson… - Nucleic Acids …, 2023 - academic.oup.com
In Bacteria, nucleoid structuring proteins govern nucleoid dynamics and regulate
transcription. In Shigella spp., at≤ 30° C, the histone-like nucleoid structuring protein (H-NS) …
transcription. In Shigella spp., at≤ 30° C, the histone-like nucleoid structuring protein (H-NS) …
A New Role of OmpR in Acid and Osmotic Stress in Salmonella and E. coli
S Chakraborty, LJ Kenney - Frontiers in microbiology, 2018 - frontiersin.org
Bacteria survive and respond to diverse environmental conditions and during infection
inside the host by systematic regulation of stress response genes. E. coli and S …
inside the host by systematic regulation of stress response genes. E. coli and S …
Integration of a complex regulatory cascade involving the SirA/BarA and Csr global regulatory systems that controls expression of the Salmonella SPI‐1 and SPI‐2 …
LC Martínez, H Yakhnin, MI Camacho… - Molecular …, 2011 - Wiley Online Library
Salmonella pathogenicity islands 1 and 2 (SPI‐1 and SPI‐2) play key roles in the
pathogenesis of Salmonella enterica. Previously, we showed that when Salmonella grows in …
pathogenesis of Salmonella enterica. Previously, we showed that when Salmonella grows in …
Charged residues in the H-NS linker drive DNA binding and gene silencing in single cells
Y Gao, YH Foo, RS Winardhi, Q Tang… - Proceedings of the …, 2017 - National Acad Sciences
Nucleoid-associated proteins (NAPs) facilitate chromosome organization in bacteria, but the
precise mechanism remains elusive. H-NS is a NAP that also plays a major role in silencing …
precise mechanism remains elusive. H-NS is a NAP that also plays a major role in silencing …
Transcription of bacterial chromatin
BA Shen, R Landick - Journal of molecular biology, 2019 - Elsevier
Decades of research have probed the interplay between chromatin (genomic DNA
associated with proteins and RNAs) and transcription by RNA polymerase (RNAP) in all …
associated with proteins and RNAs) and transcription by RNA polymerase (RNAP) in all …
H-NS regulates gene expression and compacts the nucleoid: insights from single-molecule experiments
A set of abundant nucleoid-associated proteins (NAPs) play key functions in organizing the
bacterial chromosome and regulating gene transcription globally. Histone-like nucleoid …
bacterial chromosome and regulating gene transcription globally. Histone-like nucleoid …
A Fundamental Regulatory Mechanism Operating through OmpR and DNA Topology Controls Expression of Salmonella Pathogenicity Islands SPI-1 and SPI-2
ADS Cameron, CJ Dorman - PLoS Genetics, 2012 - journals.plos.org
DNA topology has fundamental control over the ability of transcription factors to access their
target DNA sites at gene promoters. However, the influence of DNA topology on protein …
target DNA sites at gene promoters. However, the influence of DNA topology on protein …