An α-chloroaldehyde-based formal synthesis of eribulin
A Kaghad, D Panagopoulos… - Nature …, 2023 - nature.com
Eribulin (Halaven) is the most structurally complex non-peptidic drug made by total synthesis
and has challenged preconceptions of synthetic feasibility in drug discovery and …
and has challenged preconceptions of synthetic feasibility in drug discovery and …
Strategies for Carbon Electrophile Addition to Carbonyls and Imines by Cobalt Catalysis
B Kokić, B Vulović, M Jović, A Andrijević… - European Journal of …, 2023 - Wiley Online Library
The addition of carbon electrophiles to carbonyls and imines has emerged as a valuable
strategy for the construction of C− C bonds. The merger of this concept with sustainable …
strategy for the construction of C− C bonds. The merger of this concept with sustainable …
Photocatalytic Cleavage of Trityl Protected Thiols and Alcohols
S Murakami, C Brudy, M Bachmann, Y Takemoto… - …, 2023 - thieme-connect.com
We report the visible light photocatalytic cleavage of trityl thioethers or ethers under pH-
neutral conditions. The method results in the formation of the respective symmetrical …
neutral conditions. The method results in the formation of the respective symmetrical …
[PDF][PDF] Visible-light-mediated Oxidative Debenzylation of 3-O-Benzyl-1, 2: 5, 6-di-O-isopropylidene-α-D-glucofuranose
1, 2: 5, 6-Di-O-isopropylidene-α-D-glucofuranose (1). An oven-dried, singlenecked side-
armed Schlenk tube (250 mL, 23 x 4.5 cm) equipped with a football-shaped Teflon-coated …
armed Schlenk tube (250 mL, 23 x 4.5 cm) equipped with a football-shaped Teflon-coated …
[PDF][PDF] 単体硫黄のレドックス特性を利用した含硫黄化合物合成法と可視光レドックス触媒系による新規脱保護法の開発
村上翔 - 2023 - repository.kulib.kyoto-u.ac.jp
第 1 章 総論近年, 複雑分子にも適用可能な高化学選択的反応が有機合成において強く望まれて
いる. そのため, 温和な反応条件下で様々な活性化学種を発生させ, かつその化学種を精密に反応 …
いる. そのため, 温和な反応条件下で様々な活性化学種を発生させ, かつその化学種を精密に反応 …